Anti-Cortisol 抗体 [CORT-2] (ab1952)

製品の概要

  • 製品名Anti-Cortisol antibody [CORT-2]
    Cortisol 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [CORT-2] to Cortisol
  • 特異性Cortisol-BSA conjugate and free cortisol. There is no cross-reactivity with BSA. CORT-2 does not bind with cortisone.
  • アプリケーション適用あり: competitive binding assaysmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein (Human) conjugated to BSA.

  • 特記事項Concentration varies from lot to lot and can be provided on request.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)Purity tested by elcetrophoresis.
  • ポリ/モノモノクローナル
  • クローン名CORT-2
  • ミエローマSp2/0
  • アイソタイプIgG3
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab1952 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
competitive binding assays Use at an assay dependent dilution.

ターゲット情報

  • 関連性Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.
  • 細胞内局在Secreted

Anti-Cortisol antibody [CORT-2] 画像

  • Cross-reactivity, % 50% displacement of cortisol-3-125-Iodine.

Anti-Cortisol antibody [CORT-2] (ab1952) 使用論文

ab1952 has not yet been referenced specifically in any publications.

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Thank you for contacting us.

To be honest we do not have an antibody that we have tested with this kind of novel assay, and therefore do not know if it would work nor can we guarantee it.

Although ab1949 may work, I may recommend ab...

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Cross-reaction of cortisol antibodies with cortisone is the following: ab1949 - 0.6 %, ab1951 - 35 % and ab1952 - 0 %.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"