製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to CORO1B
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residue 450 and 489 of human CORO1B (NP_065174.1).

  • ポジティブ・コントロール
    • Human Controls: Breast Carcinoma, Ovarian Carcinoma, Prostate Carcinoma, Stomach Carcinoma and Skin Squamous Cell Carcinoma.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84558 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報
    IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction.
    • 配列類似性
      Belongs to the WD repeat coronin family.
      Contains 5 WD repeats.
    • 翻訳後修飾
      Phosphorylation by PKC on Ser-2 regulates the interaction with the Arp2/3 complex and cell motility in fibroblasts. Phosphorylation does not seem to affect subcellular location.
    • 細胞内局在
      Cytoplasm > cytoskeleton. Localized to the leading edge in fibroblasts, as well as weakly along actin stress fibers.
    • Information by UniProt
    • 参照データベース
    • 別名
      • COR1B_HUMAN antibody
      • CORO 1B antibody
      • CORO1B antibody
      • Coronin 1B antibody
      • Coronin 2 antibody
      • Coronin actin binding protein 1B antibody
      • Coronin-1B antibody
      • Coronin-2 antibody
      • Coronin1B antibody
      • Coronin2 antibody
      • DKFZP762I166 antibody
      • OTTHUMP00000236823 antibody
      see all

    画像

    • ab84558, at a 1/250 dilution, staining CORO1B in formalin fixed, paraffin embedded human prostate carcinoma by Immunohistochemistry, using DAB detection.
    • ab84558, at a 1/250 dilution, staining CORO1B in formalin fixed, paraffin embedded human stomach carcinoma by Immunohistochemistry, using DAB detection.

    プロトコール

    参考文献

    ab84558 has not yet been referenced specifically in any publications.

    レビューと Q&A

    There are currently no Customer reviews or Questions for ab84558.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    登録