製品の概要

  • 製品名Anti-Corneodesmosin antibody
    Corneodesmosin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Corneodesmosin
  • アプリケーション適用あり: WB, IHC-P, IHC-Frmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide derived from Nter domain of human CDSN

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium azide
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab118835 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Predicted molecular weight: 51 kDa.
IHC-P Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

ターゲット情報

  • 機能Important for the epidermal barrier integrity.
  • 組織特異性Exclusively expressed in skin.
  • 関連疾患Defects in CDSN are a cause of hypotrichosis simplex of the scalp (HTSS) [MIM:146520]; also known as hypotrichosis Spanish type. HTSS is an autosomal dominant form of isolated alopecia. Affected individuals have normal hair in early childhood but experience progressive loss of scalp hair beginning in the middle of the first decade and almost complete baldness by the third decade.
    Defects in CDSN are the cause of peeling skin syndrome type B (BPSS) [MIM:270300]; also known as peeling skin syndrome or deciduous skin or keratolysis exfoliativa congenita. BPSS is a genodermatosis characterized by the continuous shedding of the outer layers of the epidermis, associated with pruritus and atopy. It is an ichthyosiform erythroderma characterized by lifelong patchy peeling of the entire skin with onset at birth or shortly thereafter. Several patients have been reported with high IgE levels.
  • 細胞内局在Secreted. Found in corneodesmosomes, the intercellular structures that are involved in desquamation.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AI747712 antibody
    • CDSN antibody
    • CDSN_HUMAN antibody
    • Corneodesmosin antibody
    • D6S586E antibody
    • DADB-141O4.5 antibody
    • Differentiated keratinocyte S protein antibody
    • HTSS antibody
    • S antibody
    • S protein antibody
    see all

Anti-Corneodesmosin antibody (ab118835) 使用論文

ab118835 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"