製品の概要

  • 製品名Anti-Corin antibody
    Corin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Corin
  • アプリケーション適用あり: WB, IP, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 60-150 of Mouse Corin.

  • ポジティブ・コントロール
    • Whole cell lysates derived from Mouse heart and Rat heart

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーpH: 7.20
    Constituent: 99% PBS
    Note: antibody stabilizer(10mg/ml BSA,0.05% proclin300 in PBS)
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)The Rabbit IgG is purified by Epitope Affinity Purification.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab125254 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.1 - 1 µg/ml. Detects a band of approximately 120, 250 kDa (predicted molecular weight: 116 kDa).
IP Use a concentration of 2 - 5 µg/ml.
ELISA Use a concentration of 0.01 - 0.1 µg/ml.
IHC-P Use a concentration of 2 - 10 µg/ml.

ターゲット情報

  • 機能Serine-type endopeptidase involved in atrial natriuretic peptide hormone processing. Converts through proteolytic cleavage the non-functional propeptide NPPA/ANP into the active hormone which promotes natriuresis, diuresis, and vasodilatation. May also process pro-NPPB the B-type natriuretic peptide.
  • 組織特異性Highly expressed in heart. Expressed in heart myocytes.
  • 配列類似性Belongs to the peptidase S1 family.
    Contains 2 FZ (frizzled) domains.
    Contains 7 LDL-receptor class A domains.
    Contains 1 peptidase S1 domain.
    Contains 1 SRCR domain.
  • 翻訳後修飾N-glycosylated; required for processing and activation.
    Activated through proteolytic processing by a trypsin-like protease; cleaved into a N-terminal propeptide and an activated corin protease fragment.
    A disulfide bond links the N-terminal propeptide and the activated corin protease fragment.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • activated protease fragment antibody
    • ATC 2 antibody
    • ATC2 antibody
    • Atrial natriuretic peptide-converting enzyme antibody
    • Atrial natriuteric peptide converting enzyme antibody
    • Corin antibody
    • Corin serine peptidase antibody
    • CORIN_HUMAN antibody
    • CRN antibody
    • Heart specific serine proteinase antibody
    • Heart specific serine proteinase ATC2 antibody
    • Heart-specific serine proteinase ATC2 antibody
    • Lrp 4 antibody
    • Lrp4 antibody
    • MGC119742 antibody
    • Pro ANP convertase antibody
    • Pro ANP converting enzyme antibody
    • Pro-ANP-converting enzyme antibody
    • TMPRSS 10 antibody
    • TMPRSS10 antibody
    • Transmembrane protease serine 10 antibody
    see all

Anti-Corin antibody 画像

  • All lanes : Anti-Corin antibody (ab125254) at 1/500 dilution

    Lane 1 : Mouse heart whole cell lysates
    Lane 2 : Rat heart whole cell lysates


    Predicted band size : 116 kDa
    Observed band size : 120 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 205 kDa. We are unsure as to the identity of these extra bands.

Anti-Corin antibody (ab125254) 使用論文

ab125254 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab125254.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"