製品の概要

  • 製品名Anti-COQ2 antibody
    COQ2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to COQ2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Cat, Dog, Pig, Saccharomyces cerevisiae, Drosophila melanogaster, Zebrafish
  • 免疫原

    Synthetic peptide within residues: SGVMWTLIYD TIYAHQDKRD DVLIGLKSTA LRFGENTKPW LSGFSVAMLG, corresponding to internal sequence amino acids 252-301 of Human COQ2 (NP_056512)

  • ポジティブ・コントロール
    • DU145 cell lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab89706 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 40 kDa.Can be blocked with COQ2 peptide (ab175788). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB.
  • 組織特異性Widely expressed. Present in all of the tissues tested. Expressed at higher level in skeletal muscle, adrenal glands and the heart.
  • パスウェイCofactor biosynthesis; ubiquinone biosynthesis.
  • 関連疾患Defects in COQ2 are the cause of coenzyme Q10 deficiency, primary, type 1 (COQ10D1) [MIM:607426]. An autosomal recessive disorder with variable manifestations consistent with 5 major phenotypes. The phenotypes include an encephalomyopathic form with seizures and ataxia; a multisystem infantile form with encephalopathy, cardiomyopathy and renal failure; a predominantly cerebellar form with ataxia and cerebellar atrophy; Leigh syndrome with growth retardation; and an isolated myopathic form.
  • 配列類似性Belongs to the UbiA prenyltransferase family.
  • 細胞内局在Mitochondrion membrane.
  • Information by UniProt
  • 参照データベース
    see all
  • 別名
    • 2310002F18Rik antibody
    • 4-hydroxybenzoate polyprenyltransferase antibody
    • CL640 antibody
    • Coenzyme Q2 4-hydroxybenzoate polyprenyltransferase antibody
    • Coenzyme Q2 homolog, prenyltransferase (yeast) antibody
    • COQ10D1 antibody
    • COQ2 antibody
    • COQ2 homolog antibody
    • COQ2_HUMAN antibody
    • FLJ13014 antibody
    • FLJ26072 antibody
    • hCOQ2 antibody
    • MGC124824 antibody
    • MGC91278 antibody
    • mitochondrial antibody
    • MSA1 antibody
    • OTTMUSP00000032111 antibody
    • Para-hydroxybenzoate--polyprenyltransferase antibody
    • Para-hydroxybenzoate--polyprenyltransferase, mitochondrial antibody
    • PHB:polyprenyltransferase antibody
    • RGD1306722 antibody
    see all

Anti-COQ2 antibody 画像

  • Anti-COQ2 antibody (ab89706) at 1 µg/ml + DU145 cell lysate at 10 µg

    Secondary
    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size : 40 kDa
    Observed band size : 40 kDa

Anti-COQ2 antibody (ab89706) 使用論文

ab89706 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab89706.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"