製品の概要

  • 製品名Anti-COPZ1 antibody
    COPZ1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to COPZ1
  • アプリケーション適用あり: ELISA, WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide derived from an internal sequence of human COPZ1.

  • ポジティブ・コントロール
    • Human cervix carcinoma tissue. Jurkat and COS cell extracts.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab74370 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/10000.
WB 1/500 - 1/1000. Detects a band of approximately 20 kDa (predicted molecular weight: 20 kDa).
IHC-P 1/50 - 1/100.

ターゲット情報

  • 機能The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
    The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
  • 配列類似性Belongs to the adaptor complexes small subunit family.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Cytoplasm. Golgi apparatus membrane. Cytoplasmic vesicle > COPI-coated vesicle membrane. The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5930435A22Rik antibody
    • AA407760 antibody
    • CGI 120 antibody
    • Coatomer protein complex subunit zeta 1 antibody
    • Coatomer subunit zeta 1 antibody
    • Coatomer subunit zeta-1 antibody
    • COPZ antibody
    • COPZ 1 antibody
    • COPZ1 antibody
    • COPZ1_HUMAN antibody
    • D4Ertd360e antibody
    • HSPC181 antibody
    • MGC118060 antibody
    • Zeta 1 coat protein antibody
    • zeta 1 COP antibody
    • zeta COP antibody
    • Zeta-1 COP antibody
    • Zeta-1-coat protein antibody
    • Zeta1 COP antibody
    see all

Anti-COPZ1 antibody 画像

  • ab74370 at 1/50 dilution staining COPZ1 in human cervix carcinoma by Immunohistochemistry using paraffin-embedded tissue, in the absence or presence of the immunising peptide.
  • All lanes : Anti-COPZ1 antibody (ab74370) at 1/500 dilution

    Lane 1 : Jurkat cell extracts
    Lane 2 : COS cell extracts
    Lane 3 : Jurkat cell extracts with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 20 kDa
    Observed band size : 20 kDa
    Additional bands at : 28 kDa,36 kDa,47 kDa,82 kDa. We are unsure as to the identity of these extra bands.

Anti-COPZ1 antibody (ab74370) 使用論文

ab74370 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"