製品の概要

  • 製品名Anti-COPS8 antibody
    COPS8 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to COPS8
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to a 15 amino acid peptide near the carboxy terminus of Human COPS8 (NP_006701).

  • ポジティブ・コントロール
    • Human liver lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab106560 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 23 kDa.

ターゲット情報

  • 機能Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
  • 配列類似性Belongs to the CSN8 family.
    Contains 1 PCI domain.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • COP9 homolog antibody
    • COP9 signalosome complex subunit 8 antibody
    • COP9 signalosome subunit 8 antibody
    • Cops8 antibody
    • CSN8 antibody
    • CSN8_HUMAN antibody
    • hCOP9 antibody
    • JAB1 containing signalosome subunit 8 antibody
    • JAB1-containing signalosome subunit 8 antibody
    • SGN8 antibody
    • Signalosome subunit 8 antibody
    see all

Anti-COPS8 antibody 画像

  • Anti-COPS8 antibody (ab106560) at 2 µg/ml + Human liver lysate at 15 µg

    Predicted band size : 23 kDa

Anti-COPS8 antibody (ab106560) 使用論文

ab106560 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab106560.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"