Anti-Connexin 45/GJA7/Cx45 抗体 (ab16588)
Key features and details
- Sheep polyclonal to Connexin 45/GJA7/Cx45
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Connexin 45/GJA7/Cx45 antibody
Connexin 45/GJA7/Cx45 一次抗体 製品一覧 -
製品の詳細
Sheep polyclonal to Connexin 45/GJA7/Cx45 -
由来種
Sheep -
特異性
Does not cross react with Connexins 37, 40 or 43. -
アプリケーション
適用あり: ICC/IFmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Hamster, Dog -
免疫原
Synthetic peptide corresponding to Human Connexin 45/GJA7/Cx45 aa 354-367.
Sequence:QAYSHQNNPHGPRE
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ポジティブ・コントロール
- Cos-7 cells transfected with Connexin 45/GJA7/Cx45 cDNA.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7
Constituent: Whole serum -
Concentration information loading...
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精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab16588の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ICC/IF |
Use at an assay dependent concentration.
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特記事項 |
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ICC/IF
Use at an assay dependent concentration. |
ターゲット情報
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機能
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. -
配列類似性
Belongs to the connexin family. Gamma-type subfamily. -
細胞内局在
Cell membrane. Cell junction > gap junction. - Information by UniProt
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参照データベース
- Entrez Gene: 490936 Dog
- Entrez Gene: 10052 Human
- Entrez Gene: 14615 Mouse
- Entrez Gene: 266706 Rat
- Omim: 608655 Human
- SwissProt: P28228 Dog
- SwissProt: P36383 Human
- SwissProt: P28229 Mouse
see all -
別名
- Connexin 45 / GJA7 antibody
- Connexin 45 antibody
- Connexin-45 antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (2)
ab16588 は 2 報の論文で使用されています。
- Langhorst H et al. The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice. Dis Model Mech 11:N/A (2018). PubMed: 29361518
- Mansour H et al. Connexin 30 expression and frequency of connexin heterogeneity in astrocyte gap junction plaques increase with age in the rat retina. PLoS One 8:e57038 (2013). WB, IHC ; Mouse, Rat . PubMed: 23516399