Anti-Complement factor 8 beta 抗体 (ab111700)

製品の概要

  • 製品名
    Anti-Complement factor 8 beta antibody
    Complement factor 8 beta 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Complement factor 8 beta
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rabbit
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 412-563 of Human Complement factor 8 beta (AAI30576).

  • ポジティブ・コントロール
    • HeLa, HepG2 and HCT116 whole cell lysates.

法規制情報

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1% BSA, 20% Glycerol, PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab111700 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Predicted molecular weight: 67 kDa.

ターゲット情報

  • 機能
    Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
  • 関連疾患
    Defects in C8B are a cause of complement component 8 deficiency type 2 (C8D2) [MIM:120960]. A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
  • 配列類似性
    Belongs to the complement C6/C7/C8/C9 family.
    Contains 1 EGF-like domain.
    Contains 1 LDL-receptor class A domain.
    Contains 1 MACPF domain.
    Contains 2 TSP type-1 domains.
  • 翻訳後修飾
    N-glycosylated; contains one or two bound glycans. Not O-glycosylated.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C8b antibody
    • CO8B_HUMAN antibody
    • Complement component 8 beta polypeptide antibody
    • Complement component 8 subunit beta antibody
    • Complement component C8 beta chain antibody
    see all

画像

  • Anti-Complement factor 8 beta antibody (ab111700) at 1/5000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 67 kDa

プロトコール

参考文献

ab111700 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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