Anti-Collagen VII 抗体 [2Q636] (ab64566)

製品の概要

  • 製品名Anti-Collagen VII antibody [2Q636]
    Collagen VII 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2Q636] to Collagen VII
  • 特異性ab64566 recognizes carboxy terminal peptide of type VII collagen.
  • アプリケーション適用あり: ELISA, IHC-Frmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human Collagen type VII

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 40% for extra stability and aliquot. Store at -20°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.1% Sodium Azide
  • Concentration information loading...
  • 精製度Ascites
  • ポリ/モノモノクローナル
  • クローン名2Q636
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab64566 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution.
IHC-Fr Use at an assay dependent dilution.

ターゲット情報

  • 機能Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.
  • 関連疾患Epidermolysis bullosa acquisita (EBA) is an autoimmune acquired blistering skin disease resulting from autoantibodies to type VII collagen.
    Epidermolysis bullosa dystrophica, autosomal dominant
    Epidermolysis bullosa dystrophica, autosomal recessive
    Epidermolysis bullosa dystrophica, Pasini type
    Epidermolysis bullosa dystrophica, Hallopeau-Siemens type
    Transient bullous dermolysis of the newborn
    Epidermolysis bullosa dystrophica, pretibial type
    Epidermolysis bullosa dystrophica, Bart type
    Epidermolysis bullosa pruriginosa
    Nail disorder, non-syndromic congenital, 8
    Epidermolysis bullosa dystrophica, with subcorneal cleavage
  • 配列類似性Contains 1 BPTI/Kunitz inhibitor domain.
    Contains 9 fibronectin type-III domains.
    Contains 2 VWFA domains.
  • 翻訳後修飾Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
  • 細胞内局在Secreted > extracellular space > extracellular matrix > basement membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Alpha 1 type VII collagen antibody
    • CO7A1_HUMAN antibody
    • Col7a1 antibody
    • Collagen alpha 1(VII) chain antibody
    • Collagen alpha-1(VII) chain antibody
    • Collagen type VII alpha 1 antibody
    • Collagen VII alpha 1 polypeptide antibody
    • CollagenVII antibody
    • EBD 1 antibody
    • EBD1 antibody
    • EBDCT antibody
    • EBR 1 antibody
    • EBR1 antibody
    • LC collagen antibody
    • Long chain collagen antibody
    • Long-chain collagen antibody
    see all

Anti-Collagen VII antibody [2Q636] (ab64566) 使用論文

ab64566 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. I can confirm that this product can detect the NC-1 domain. Unfortunately, the epitope sequence has not been identified but is located at the C-terminus.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"