Anti-Collagen VI 抗体 (Biotin) (ab119300)

製品の概要

  • 製品名Anti-Collagen VI antibody (Biotin)
    Collagen VI 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Collagen VI (Biotin)
  • 標識Biotin
  • アプリケーション適用あり: WB, IP, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: all Mammals
  • 免疫原

    The immunogen is collagen type VI purified from human and bovine placenta

  • ポジティブ・コントロール
    • Human liver or prostate tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab119300 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/5000 - 1/10000. Predicted molecular weight: 109 kDa.
IP Use at an assay dependent dilution.
ELISA 1/10000 - 1/50000.
IHC-P Use a concentration of 1.25 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Collagen VI acts as a cell-binding protein.
  • 関連疾患Defects in COL6A1 are a cause of Bethlem myopathy (BM) [MIM:158810]. BM is a rare autosomal dominant proximal myopathy characterized by early childhood onset (complete penetrance by the age of 5) and joint contractures most frequently affecting the elbows and ankles.
    Defects in COL6A1 are a cause of Ullrich congenital muscular dystrophy (UCMD) [MIM:254090]; also known as Ullrich scleroatonic muscular dystrophy. UCMD is an autosomal recessive congenital myopathy characterized by muscle weakness and multiple joint contractures, generally noted at birth or early infancy. The clinical course is more severe than in Bethlem myopathy.
  • 配列類似性Belongs to the type VI collagen family.
    Contains 3 VWFA domains.
  • 翻訳後修飾Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
  • 細胞内局在Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Alpha 1 (VI) chain (61 AA) antibody
    • CO6A1_HUMAN antibody
    • COL6A1 antibody
    • COL6A2 antibody
    • COL6A3 antibody
    • Collagen alpha 2(VI) chain antibody
    • Collagen alpha 3(VI) chain antibody
    • Collagen alpha-1(VI) chain antibody
    • Collagen type VI alpha 1 antibody
    • Collagen type VI alpha 2 antibody
    • Collagen type VI alpha 3 antibody
    • Collagen VI alpha 1 polypeptide antibody
    • Collagen VI alpha 2 polypeptide antibody
    • Collagen VI alpha 3 polypeptide antibody
    • CollagenVI antibody
    • Human mRNA for collagen VI alpha 2 C terminal globular domain antibody
    • OPLL antibody
    • PP3610 antibody
    see all

Anti-Collagen VI antibody (Biotin) 画像

  • ab119300, at a 1.25µg/ml, staining Human Collagen VI in liver, using Immunohistochemistry, Formalin/PFA-fixed parraffin-embedded tissue.
  • ab119300, at a 1.25µg/ml, staining Human Collagen VI in prostate, using Immunohistochemistry, Formalin/PFA-fixed parraffin-embedded tissue.

Anti-Collagen VI antibody (Biotin) (ab119300) 使用論文

ab119300 has not yet been referenced specifically in any publications.

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Thank you for contacting Abcam regarding finding biotin labeled primary antibodies and control tissues.

After review of our catalog, my first recommendation is anti-Collagen VI, ab119300. This product is guaranteed in IHC-P and the images on...

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