製品の概要

  • 製品名Anti-Colec12 antibody
    Colec12 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Colec12
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 109-158 (LSTFRSDILD LRQQLREITE KTSKNKDTLE KLQASGDALV DRQSQLKETL) of Human Colec12 (NP_569057).

  • ポジティブ・コントロール
    • 721_B cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab81136 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 82 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

Titre using peptide based assay: 1/1562500.

ターゲット情報

  • 機能Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). May also play a role in the clearance of amyloid beta in Alzheimer disease.
  • 組織特異性Expressed in perivascular macrophages. Expressed in plaques-surrounding reactive astrocytes and in perivascular astrocytes associated with cerebral amyloid angiopathy (CAA) in the temporal cortex of Alzheimer patient (at protein level). Strongly expressed in placenta. Moderately expressed in heart, skeletal muscle, small intestine and lung. Weakly expressed in brain, colon, thymus and kidney. Expressed in nurse-like cells. Expressed in reactive astrocytes and vascular/perivascular cells in the brain of Alzheimer patient.
  • 配列類似性Contains 1 C-type lectin domain.
    Contains 3 collagen-like domains.
  • 細胞内局在Membrane. Forms clusters on the cell surface.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CL P1 antibody
    • CL-P1 antibody
    • CLP1 antibody
    • COL12_HUMAN antibody
    • COLEC 12 antibody
    • colec12 antibody
    • Collectin placenta 1 antibody
    • Collectin placenta protein 1 antibody
    • Collectin sub family member 12 antibody
    • Collectin-12 antibody
    • hCL P1 antibody
    • hCL-P1 antibody
    • NSR2 antibody
    • Nurse cell scavenger receptor 2 antibody
    • SCARA4 antibody
    • Scavenger receptor class A member 4 antibody
    • Scavenger receptor with C type lectin antibody
    • Scavenger receptor with C-type lectin antibody
    • SRCL antibody
    see all

Anti-Colec12 antibody 画像

  • Anti-Colec12 antibody (ab81136) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 82 kDa
    Observed band size : 82 kDa

Anti-Colec12 antibody (ab81136) 使用論文

ab81136 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab81136.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"