製品の概要

  • 製品名Anti-COG7 antibody
    COG7 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to COG7
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Dog, Cynomolgus Monkey, Orangutan
  • 免疫原

    Synthetic peptide:

    C-KTRPEDYRQVSK

    , corresponding to internal sequence amino acids 741-752 of Human COG7 (NP_705831.1)

  • ポジティブ・コントロール
    • HeLa, Jurkat or MOLT4 golgi lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified from goat serum by ammonium sulphate precipitation, followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab77539 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 85 kDa.
    Peptide ELISA: antibody detection limit dilution 1:32,000.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Required for normal Golgi function.
    • 関連疾患Defects in COG7 are the cause of congenital disorder of glycosylation type 2E (CDG2E) [MIM:608779]. CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
    • 配列類似性Belongs to the COG7 family.
    • 細胞内局在Golgi apparatus membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CDG2E antibody
      • COG complex subunit 7 antibody
      • cog7 antibody
      • COG7_HUMAN antibody
      • Component of oligomeric Golgi complex 7 antibody
      • Conserved oligomeric Golgi complex component 7 antibody
      • Conserved oligomeric Golgi complex subunit 7 antibody
      see all

    Anti-COG7 antibody 画像

    Anti-COG7 antibody (ab77539) 使用論文

    ab77539 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab77539.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"