製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to Cofilin
  • 特異性
    ab29038 recognises Cofilin 1. The immunogen sequence has only 3 amino acid differences from human Cofilin 2.
  • アプリケーション
    適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide (conjugated to KLH) corresponding to amino acid residues at the N terminus of human Cofilin 1.

  • ポジティブ・コントロール
    • Jurkat cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab29038 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/2000.
WB 1/1000. Predicted molecular weight: 18 kDa.Can be blocked with Human Cofilin peptide (ab37634).

ターゲット情報

  • 機能
    Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
  • 組織特異性
    Widely distributed in various tissues.
  • 配列類似性
    Belongs to the actin-binding proteins ADF family.
    Contains 1 ADF-H domain.
  • 翻訳後修飾
    Phosphorylated on Ser-3 in resting cells.
  • 細胞内局在
    Nucleus matrix. Cytoplasm > cytoskeleton. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 18 kDa phosphoprotein antibody
    • CFL 1 antibody
    • CFL antibody
    • CFL1 antibody
    • COF1_HUMAN antibody
    • Cofilin 1 antibody
    • Cofilin 1 non muscle antibody
    • Cofilin antibody
    • Cofilin non muscle isoform antibody
    • Cofilin-1 antibody
    • epididymis secretory protein Li 15 antibody
    • HEL-S-15 antibody
    • non-muscle isoform antibody
    • p18 antibody
    see all

画像



  • Predicted band size : 18 kDa

プロトコール

参考文献

This product has been referenced in:
  • Kamal AH  et al. Investigation of adipocyte proteome during the differentiation of brown preadipocytes. J Proteomics 94:327-36 (2013). Read more (PubMed: 24129212) »
  • Codreanu SG  et al. Global analysis of protein damage by the lipid electrophile 4-hydroxy-2-nonenal. Mol Cell Proteomics 8:670-80 (2009). WB ; Human . Read more (PubMed: 19054759) »

See all 2 Publications for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab29038.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録