Anti-CNTF Receptor alpha 抗体 (ab58560)
製品の概要
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製品名Anti-CNTF Receptor alpha antibody
CNTF Receptor alpha 一次抗体 製品一覧 -
製品の詳細Goat polyclonal to CNTF Receptor alpha
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特異性This antibody is expected to recognise both reported isoforms (NP_671693.1; NP_001833.1).
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アプリケーション適用あり: WBmore details
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種交差性交差種: Mouse, Rat, Human
交差が予測される動物種: Chicken, Dog, Pufferfish, Zebrafish
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免疫原
Synthetic peptide:
CRSNTYPKGFY
, corresponding to internal sequence amino acids 116-126 of Human CNTF Receptor alpha -
ポジティブ･コントロール
- Mouse Brain lysate.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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バッファーPreservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris saline, pH 7.3 -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab58560 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa). |
ターゲット情報
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機能Binds to CNTF. The alpha subunit provides the receptor specificity.
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組織特異性Nervous system and skeletal muscle.
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配列類似性Belongs to the type I cytokine receptor family. Type 3 subfamily.
Contains 2 fibronectin type-III domains.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain. -
ドメインThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
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細胞内局在Cell membrane.
- Information by UniProt
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参照データベース
- Entrez Gene: 1271 Human
- Entrez Gene: 12804 Mouse
- Entrez Gene: 313173 Rat
- Omim: 118946 Human
- SwissProt: Q71DR4 Dog
- SwissProt: P26992 Human
- SwissProt: O88507 Mouse
- SwissProt: Q08406 Rat
see all -
別名
- Ciliary neurotrophic factor receptor alpha antibody
- Ciliary neurotrophic factor receptor antibody
- Ciliary neurotrophic factor receptor subunit alpha antibody
see all
Anti-CNTF Receptor alpha antibody 画像
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Western blot - CNTF Receptor alpha antibody (ab58560)Anti-CNTF Receptor alpha antibody (ab58560) at 0.3 µg/ml + Mouse Brain lysate (35µg protein in RIPA buffer)
Predicted band size : 41 kDa
Observed band size : 41 kDa -
Western blot - CNTF Receptor alpha antibody (ab58560)All lanes : Anti-CNTF Receptor alpha antibody (ab58560) at 1 µg/ml
Lane 1 : Human skeletal muscle tissue lysate - total protein (ab29330) at 20 µg
Lane 2 :Mouse skeletal muscle tissue lysate - total protein (ab29711) at 20 µg
Lane 3 : Skeletal Muscle (Rat) Tissue Lysate - normal tissue (ab29376) at 20 µg
Lane 4 : Human brain tissue lysate - total protein (ab29466) at 10 µg
Lane 5 : Brain (Mouse) Tissue Lysate (ab27253) at 10 µg
Lane 6 : Brain (Rat) Tissue Lysate (ab7942) at 10 µg
Secondary
Rabbit polyclonal to Goat IgG - H&L - Pre-Adsorbed (HRP) (ab65486) at 1/3000 dilution
Predicted band size : 41 kDa
プロトコール
Anti-CNTF Receptor alpha antibody (ab58560) 使用論文
This product has been referenced in:
- Li R et al. CNTF Mediates Neurotrophic Factor Secretion and Fluid Absorption in Human Retinal Pigment Epithelium. PLoS One 6:e23148 (2011). WB ; Human . Read more (PubMed: 21912637) »
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"