The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
CCHC type zinc finger nucleic acid binding protein
Cellular nucleic acid binding protein
Cellular nucleic acid-binding protein
Erythroid differentiation related
Proximal myotonic myopathy nucleic acid binding protein
Sterol regulatory element binding protein
Zinc finger protein 273
Zinc finger protein 9
Zinc finger protein 9 (a cellular retroviral nucleic acid binding protein)
機能Single stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression.
組織特異性Present in all tissues examined.
関連疾患Defects in CNBP are the cause of dystrophia myotonica type 2 (DM2) [MIM:602668]; also known as proximal myotonic myopathy (PROMM). A multisystem disease characterized by the association of proximal muscle weakness with myotonia, cardiac manifestations and cataract. Additional features can include hyperhidrosis, testicular atrophy, insulin resistance and diabetes and central nervous system anomalies in rare cases. Note=The causative mutation is a CCTG expansion (mean approximately 5000 repeats) located in intron 1 of the CNBP gene.