Anti-Clostridium botulinum A Toxoid 抗体 [230F9] (ab40786)

製品の概要

  • 製品名Anti-Clostridium botulinum A Toxoid antibody [230F9]
    Clostridium botulinum A Toxoid 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [230F9] to Clostridium botulinum A Toxoid
  • 特異性BoTox-A (1280-1292) 100%; BoTox-A 100% Does not cross react with BoTox-B, BoTox-C, BoTox-E or BoTox-F (1272-1280)
  • アプリケーション適用あり: ICC/IF, Inhibition Assaymore details
  • 免疫原

    Synthetic peptide analogue of the carboxyl terminal region of BoTox-A.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: Tissue culture supernatant
  • 精製度Tissue culture supernatant
  • 特記事項(精製)Sterile filtered culture supernatant.
  • ポリ/モノモノクローナル
  • クローン名230F9
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab40786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent dilution.
Inhibition Assay Use at an assay dependent dilution. Inhibits BoTox-A binding to Neuro2A cells treated with GT1b ganglioside which can be eliminated by prior incubation with synthetic peptide immunogen.

ターゲット情報

  • 関連性Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.
  • 別名
    • Atx antibody
    • BotA antibody
    • BOTOX antibody
    • Botulinum neurotoxin type A antibody
    • Botulism A toxoid antibody
    see all

Anti-Clostridium botulinum A Toxoid antibody [230F9] (ab40786) 使用論文

ab40786 has not yet been referenced specifically in any publications.

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The immunogen of antibody ab40786 is a "synthetic peptide analogue of the carboxyl terminal region of BoTox-A", http://www.uniprot.org/uniprot/P10845.

We have not tested this antibody in WB, if y...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"