製品の概要

  • 製品名Anti-CLIC2 antibody
    CLIC2 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to CLIC2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length Human CLIC2 protein (NP_001280.3)

  • ポジティブ・コントロール
    • Human spleen tissue lysate and CLIC2 transfected 293T cell line lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab89916 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 28 kDa).

ターゲット情報

  • 機能Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.
  • 組織特異性Detected in adult brain, heart, liver, lung, spleen, stomach and testis. Expressed in fetal liver and adult skeletal muscle.
  • 配列類似性Belongs to the chloride channel CLIC family.
    Contains 1 GST C-terminal domain.
  • ドメインMembers of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
  • 細胞内局在Cytoplasm. Membrane. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Chloride intracellular channel 2 antibody
    • Chloride intracellular channel protein 2 antibody
    • CLIC 2b antibody
    • CLIC2 antibody
    • CLIC2_HUMAN antibody
    • CLIC2b antibody
    • MRXS32 antibody
    • OTTHUMP00000196471 antibody
    • XAP 121 antibody
    • XAP121 antibody
    see all

Anti-CLIC2 antibody 画像

  • Anti-CLIC2 antibody (ab89916) at 1 µg/ml + Human spleen tissue lysate at 50 µg

    Predicted band size : 28 kDa
    Observed band size : 28 kDa
    Additional bands at : 26 kDa,35 kDa. We are unsure as to the identity of these extra bands.
  • All lanes : Anti-CLIC2 antibody (ab89916) at 1 µg/ml

    Lane 1 : CLIC2 transfected 293T cell line lysate
    Lane 2 : Non-transfected 293T cell line lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 28 kDa
    Observed band size : 28 kDa

Anti-CLIC2 antibody (ab89916) 使用論文

ab89916 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"