製品の概要

  • 製品名Anti-CLEC5A antibody
    CLEC5A 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to CLEC5A
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length Human CLEC5A protein (NP_037384.1).

  • ポジティブ・コントロール
    • Human liver tissue lysate and CLEC5A transfected 293T cell line lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab89060 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 22 kDa.

ターゲット情報

  • 機能Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation (By similarity). Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
  • 組織特異性Expressed in peripheral blood monocytes and in the monocyte/macrophage cell lines U-937 and Mono-Mac-6, but not in cell lines of other origins. Expression is down-regulated when monocytes differentiate into dendritic cells.
  • 配列類似性Contains 1 C-type lectin domain.
  • 翻訳後修飾N-glycosylated. Contains sialic acid residues.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C type lectin domain family 5 member A antibody
    • C-type lectin domain family 5 member A antibody
    • C-type lectin superfamily member 5 antibody
    • CLC5A_HUMAN antibody
    • CLEC5 A antibody
    • CLEC5A antibody
    • CLECSF 5 antibody
    • CLECSF5 antibody
    • MDL 1 antibody
    • MDL-1 antibody
    • MDL1 antibody
    • Myeloid DAP12 associating lectin antibody
    • Myeloid DAP12-associating lectin 1 antibody
    see all

Anti-CLEC5A antibody 画像

  • Anti-CLEC5A antibody (ab89060) at 1 µg/ml + Human liver tissue lysate at 50 µg

    Predicted band size : 22 kDa
    Observed band size : 27 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-CLEC5A antibody (ab89060) at 1 µg/ml

    Lane 1 : CLEC5A transfected 293T cell line lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 22 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 36 kDa. We are unsure as to the identity of these extra bands.

Anti-CLEC5A antibody (ab89060) 使用論文

ab89060 has not yet been referenced specifically in any publications.

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Thank you very much for your interest our AbTrial program.

To our knowledge, ab89060 has not been tested in Flow Cytometry. However by participating in our AbTrial program you can now use our products in an untested application or species with...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"