製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to CLEC1B
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae
  • 免疫原

    Synthetic peptide corresponding to a region within N-terminal amino acids 1-50 (

    MQDEDGYITLNIKPRKQALSSAEPASSWWRVMALVLLISSMGLVVGLVAL

    ) of Mouse CLEC1B (NP_064369).

  • ポジティブ・コントロール
    • Mouse pancreas lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Constituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab116278 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets.
  • 組織特異性
    Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets.
  • 配列類似性
    Contains 1 C-type lectin domain.
  • 翻訳後修飾
    Glycosylated.
    Phosphorylated on tyrosine residue in response to rhodocytin binding.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 1810061I13Rik antibody
    • C type lectin domain family 1 member B antibody
    • C type lectin like receptor 2 antibody
    • C-type lectin domain family 1 member B antibody
    • C-type lectin domain family 1, member B antibody
    • C-type lectin-like receptor 2 antibody
    • C-type lectin-like receptor-2 antibody
    • CLC1B_HUMAN antibody
    • CLEC 2 antibody
    • CLEC 2B antibody
    • CLEC-2 antibody
    • CLEC1B antibody
    • CLEC2 antibody
    • CLEC2B antibody
    • PRO1384 antibody
    • QDED721 antibody
    see all

画像

  • Anti-CLEC1B antibody (ab116278) at 1 µg/ml + Mouse pancreas lysate at 10 µg

    Predicted band size : 27 kDa

プロトコール

参考文献

ab116278 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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