製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to CLEC12B
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 245-276 of Human CLEC12B (NP_001123470.1, NP_995324.2)

  • ポジティブ・コントロール
    • K562 cell lysate and mouse testis tissue lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab110694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 32 kDa.

ターゲット情報

  • 機能
    Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
  • 組織特異性
    Detected in colon, heart, kidney, liver, lung, mammary gland, ovary, spleen and testis.
  • 配列類似性
    Contains 1 C-type lectin domain.
  • ドメイン
    Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C-type lectin domain family 12 member B antibody
    • CL12B_HUMAN antibody
    • CLEC12B antibody
    • Macrophage antigen H antibody
    • UNQ5782 antibody
    see all

画像

  • Anti-CLEC12B antibody (ab110694) at 1/100 dilution + K562 cell lysate at 35 µg

    Predicted band size: 32 kDa

  • Anti-CLEC12B antibody (ab110694) at 1/100 dilution + Mouse testis tissue lysate at 35 µg

    Predicted band size: 32 kDa

プロトコール

参考文献

ab110694 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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