製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to CLEC12A
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, between amino acids 185-214 from the Central region of Human CLEC12A (NP_612210.4, NP_963917.2).

  • ポジティブ・コントロール
    • ZR-75-1 cell line lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    ab107494 is purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab107494 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 31 kDa.

ターゲット情報

  • 機能
    Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
  • 組織特異性
    Detected in normal myeloid cells and in acute myeloid leukemia cells. Detected in neutrophils, eosinophils, monocytes and dendritic cells. Detected in spleen macrophage-rich red pulp and in lymph node (at protein level). Detected in peripheral blood leukocytes, dendritic cells, bone marrow, monocytes, mononuclear leukocytes and macrophages.
  • 配列類似性
    Contains 1 C-type lectin domain.
  • ドメイン
    Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
  • 翻訳後修飾
    Highly N-glycosylated. Glycosylation varies between cell types.
  • 細胞内局在
    Cell membrane. Ligand binding leads to internalization.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C-type lectin domain family 12 member A antibody
    • C-type lectin-like molecule 1 antibody
    • CL12A_HUMAN antibody
    • CLEC12A antibody
    • CLL-1 antibody
    • DCAL-2 antibody
    • Dendritic cell-associated lectin 2 antibody
    • MICL antibody
    • Myeloid inhibitory C-type lectin-like receptor antibody
    see all

画像

  • Anti-CLEC12A antibody (ab107494) at 1/100 dilution + ZR-75-1 cell line lysate at 35 µg

    Predicted band size : 31 kDa

プロトコール

参考文献

ab107494 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab107494.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録