製品の概要

  • 製品名Anti-CLEC12A antibody
    CLEC12A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CLEC12A
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, between amino acids 185-214 from the Central region of Human CLEC12A (NP_612210.4, NP_963917.2).

  • ポジティブ・コントロール
    • ZR-75-1 cell line lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab107494 is purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab107494 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 31 kDa.

ターゲット情報

  • 機能Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
  • 組織特異性Detected in normal myeloid cells and in acute myeloid leukemia cells. Detected in neutrophils, eosinophils, monocytes and dendritic cells. Detected in spleen macrophage-rich red pulp and in lymph node (at protein level). Detected in peripheral blood leukocytes, dendritic cells, bone marrow, monocytes, mononuclear leukocytes and macrophages.
  • 配列類似性Contains 1 C-type lectin domain.
  • ドメインContains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
  • 翻訳後修飾Highly N-glycosylated. Glycosylation varies between cell types.
  • 細胞内局在Cell membrane. Ligand binding leads to internalization.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C-type lectin domain family 12 member A antibody
    • C-type lectin-like molecule 1 antibody
    • CL12A_HUMAN antibody
    • CLEC12A antibody
    • CLL-1 antibody
    • DCAL-2 antibody
    • Dendritic cell-associated lectin 2 antibody
    • MICL antibody
    • Myeloid inhibitory C-type lectin-like receptor antibody
    see all

Anti-CLEC12A antibody 画像

  • Anti-CLEC12A antibody (ab107494) at 1/100 dilution + ZR-75-1 cell line lysate at 35 µg

    Predicted band size : 31 kDa

Anti-CLEC12A antibody (ab107494) 使用論文

ab107494 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab107494.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"