製品の概要

  • 製品名Anti-CLCA1 antibody
    CLCA1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to CLCA1
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Macaque Monkey, Rhesus monkey
  • 免疫原

    Synthetic peptide:

    PETPSPDETSAPC

    , corresponding to internal sequence amino acids 872-884 of CLCA1 (NP_001276.2)

  • ポジティブ・コントロール
    • Human Kidney and Lung lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab77540 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/64000
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 100 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC.
    • 組織特異性Highly expressed in small intestine and colon namely in intestinal basal crypt epithelia and goblet cells, and appendix. Weakly expressed in uterus, testis and kidney. Expressed in the airways epithelium of both asthmatic andhealthy patients. Expressed in the bronchial epithelium, especially in mucus-producing goblet cells. Expressed in normal turbinate mucosa and nasal polyp. Expressed in.
    • 配列類似性Belongs to the CLCR family.
      Contains 1 VWFA domain.
    • 翻訳後修飾Glycosylated.
      The 125-kDa product is processed and yields to two cell-surface-associated subunits, a 90-kDa protein and a group of 37-to 41-kDa proteins.
    • 細胞内局在Secreted > extracellular space. Cell membrane. Protein that remains attached to the plasma membrane appeared to be predominantly localized to microvilli.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CaCC antibody
      • CaCC-1 antibody
      • CACC1 antibody
      • Calcium dependent chloride channel 1 antibody
      • Calcium-activated chloride channel family member 1 antibody
      • Calcium-activated chloride channel protein 1 antibody
      • Calcium-activated chloride channel regulator 1 antibody
      • Chloride channel calcium activated family member 1 antibody
      • Chloride channel regulator 1 antibody
      • CLCA family member 1 chloride channel regulator antibody
      • CLCA1 antibody
      • CLCA1_HUMAN antibody
      • CLCRG1 antibody
      • GOB5 antibody
      • hCaCC-1 antibody
      • hCLCA1 antibody
      see all

    Anti-CLCA1 antibody 画像

    • Anti-CLCA1 antibody (ab77540) at 0.3 µg/ml + Human lung lysate at 35 µg

      Predicted band size : 100 kDa
      Observed band size : 100 kDa

    Anti-CLCA1 antibody (ab77540) 使用論文

    ab77540 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab77540.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"