Rabbit polyclonal to Claudin18
Mouse, Rat, Rabbit, Horse, Guinea pig, Cat
Synthetic peptide corresponding to a region within amino acids 212-261 (HASGHSVAYK PGGFKASTGF GSNTKNKKIY DGGARTEDEV QSYPSKHDYV) of Human Claudin18 (NP_057453).
Human fetal thymus lysate
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
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Immunogen affinity purified
ab90671 is purified by a peptide affinity chromatography method.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 28 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Concentrated at the cell-cell borders of epithelial cells.
Belongs to the claudin family.
Cell junction > tight junction. Cell membrane.
Information by UniProt
Claudin 18 antibody
This product has been referenced in:
et al. LC-MS/MS analysis of differentially expressed glioblastoma membrane proteome reveals altered calcium signalling and other protein groups of regulatory functions. Mol Cell Proteomics : (2012).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"