Anti-Claudin 7 (phospho Y210) 抗体 (ab78198)


  • 製品名Anti-Claudin 7 (phospho Y210) antibody
    Claudin 7 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Claudin 7 (phospho Y210)
  • 特異性This antibody detects endogenous levels of Claudin 7 only when phosphorylated at tyrosine 210.
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Rat, Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthesized phosphopeptide derived from human Claudin 7 around the phosphorylation site of tyrosine 210 (S-K-E-YP-V).

  • ポジティブ・コントロール
    • Extracts from rat liver cells.


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野


Our Abpromise guarantee covers the use of ab78198 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/10000.
WB 1/500 - 1/1000. Detects a band of approximately 30 kDa (predicted molecular weight: 23 kDa).


  • 機能Plays a major role in tight junction-specific obliteration of the intercellular space.
  • 組織特異性Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions.
  • 配列類似性Belongs to the claudin family.
  • 翻訳後修飾Phosphorylated.
  • 細胞内局在Cell membrane. Lateral cell membrane. Cell junction > tight junction. Co-localizes with EPCAM at the lateral cell membrane and tight junction.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CEPTR L2 antibody
    • CEPTRL 2 antibody
    • CEPTRL2 antibody
    • Claudin 1 antibody
    • Claudin 9 antibody
    • Claudin-7 antibody
    • Claudin1 antibody
    • Claudin7 antibody
    • Claudin9 antibody
    • CLD7_HUMAN antibody
    • CLDN 7 antibody
    • CLDN-7 antibody
    • CLDN7 antibody
    • Clostridium perfringens enterotoxin receptor like 2 antibody
    • CPETR L2 antibody
    • CPETRL 2 antibody
    • CPETRL2 antibody
    • Hs.84359 antibody
    see all

Anti-Claudin 7 (phospho Y210) antibody 画像

  • All lanes : Anti-Claudin 7 (phospho Y210) antibody (ab78198) at 1/500 dilution

    Lane 1 : Extracts from rat liver cells
    Lane 2 : Extracts from rat liver cells plus 5µg immunizing peptide

    Lysates/proteins at 5 µg per lane.

    Predicted band size : 23 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)

Anti-Claudin 7 (phospho Y210) antibody (ab78198) 使用論文

ab78198 has not yet been referenced specifically in any publications.

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