製品の概要

  • 製品名Anti-Claudin 7 antibody, prediluted
    Claudin 7 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Claudin 7, prediluted
  • 特異性ab27488 recognises claudin 7.
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    A synthetic peptide from C-terminus of human claudin 7 protein

  • ポジティブ・コントロール
    • Human colon carcinoma.

製品の特性

  • 製品の状態Prediluted
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS, BSA
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab27488 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: use neat for 10 min at room temperature. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. In particular, boil tissue sections in 10mM citrate buffer pH 6.0 for 10 min and then cool at room temperature for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Plays a major role in tight junction-specific obliteration of the intercellular space.
    • 組織特異性Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions.
    • 配列類似性Belongs to the claudin family.
    • 翻訳後修飾Phosphorylated.
    • 細胞内局在Cell membrane. Lateral cell membrane. Cell junction > tight junction. Co-localizes with EPCAM at the lateral cell membrane and tight junction.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CEPTR L2 antibody
      • CEPTRL 2 antibody
      • CEPTRL2 antibody
      • Claudin 1 antibody
      • Claudin 9 antibody
      • Claudin-7 antibody
      • Claudin1 antibody
      • Claudin7 antibody
      • Claudin9 antibody
      • CLD7_HUMAN antibody
      • CLDN 7 antibody
      • CLDN-7 antibody
      • CLDN7 antibody
      • Clostridium perfringens enterotoxin receptor like 2 antibody
      • CPETR L2 antibody
      • CPETRL 2 antibody
      • CPETRL2 antibody
      • Hs.84359 antibody
      see all

    Anti-Claudin 7 antibody, prediluted 画像

    • Paraffin embedded formalin fixed human colon carcinoma tissue section stained with anti claudin 7 (ab27488).

    Anti-Claudin 7 antibody, prediluted (ab27488) 使用論文

    ab27488 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab27488.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"