Anti-Claudin 7 抗体 - C-terminal, prediluted (ab27488)

製品の概要

  • 製品名
    Anti-Claudin 7 antibody - C-terminal, prediluted
    Claudin 7 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Claudin 7 - C-terminal, prediluted
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to Human Claudin 7 (C terminal).
    Database link: O95471

  • ポジティブ・コントロール
    • IHC-P: Human colon carcinoma tissue.
  • 特記事項

    For manual IHC only.

製品の特性

  • 製品の状態
    Prediluted
  • 保存方法
    Shipped at 4°C. Store at +4°C. Do Not Freeze.
  • バッファー
    pH: 7.60
    Preservative: 0.099% Sodium azide
    Constituents: 1% BSA, Tris buffered saline
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab27488 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/1.

Ready to use.

Boil tissue section in Citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

Primary antibody incubation for 10 minutes at room temperature.

ターゲット情報

  • 機能
    Plays a major role in tight junction-specific obliteration of the intercellular space.
  • 組織特異性
    Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions.
  • 配列類似性
    Belongs to the claudin family.
  • 翻訳後修飾
    Phosphorylated.
  • 細胞内局在
    Cell membrane. Lateral cell membrane. Cell junction > tight junction. Co-localizes with EPCAM at the lateral cell membrane and tight junction.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CEPTR L2 antibody
    • CEPTRL 2 antibody
    • CEPTRL2 antibody
    • Claudin 1 antibody
    • Claudin 9 antibody
    • Claudin-7 antibody
    • Claudin1 antibody
    • Claudin7 antibody
    • Claudin9 antibody
    • CLD7_HUMAN antibody
    • CLDN 7 antibody
    • CLDN-7 antibody
    • CLDN7 antibody
    • Clostridium perfringens enterotoxin receptor like 2 antibody
    • CPETR L2 antibody
    • CPETRL 2 antibody
    • CPETRL2 antibody
    • Hs.84359 antibody
    see all

画像

  • Formalin-fixed, paraffin-embedded human colon carcinoma tissue stained for Claudin 7 using ab27488 in immunohistochemical analysis.

参考文献

ab27488 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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