Anti-Claudin 7 抗体 - C-terminal, prediluted (ab27488)
製品の概要
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製品名Anti-Claudin 7 antibody - C-terminal, prediluted
Claudin 7 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to Claudin 7 - C-terminal, prediluted
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由来種Rabbit
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アプリケーション適用あり: IHC-Pmore details
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種交差性交差種: Human
交差が予測される動物種: Mouse, Rat, Cow, Dog, Pig
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免疫原
Synthetic peptide corresponding to Human Claudin 7 (C terminal).
Database link: O95471 -
ポジティブ･コントロール
- IHC-P: Human colon carcinoma tissue.
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特記事項
For manual IHC only.
製品の特性
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製品の状態Prediluted
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保存方法Shipped at 4°C. Store at +4°C. Do Not Freeze.
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バッファーpH: 7.60
Preservative: 0.099% Sodium azide
Constituents: 1% BSA, Tris buffered saline -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
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Related Products
アプリケーション
Our Abpromise guarantee covers the use of ab27488 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P | 1/1. Ready to use. Boil tissue section in Citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min. Primary antibody incubation for 10 minutes at room temperature. |
ターゲット情報
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機能Plays a major role in tight junction-specific obliteration of the intercellular space.
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組織特異性Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions.
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配列類似性Belongs to the claudin family.
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翻訳後修飾Phosphorylated.
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細胞内局在Cell membrane. Lateral cell membrane. Cell junction > tight junction. Co-localizes with EPCAM at the lateral cell membrane and tight junction.
- Information by UniProt
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参照データベース
- Entrez Gene: 1366 Human
- Entrez Gene: 53624 Mouse
- Entrez Gene: 65132 Rat
- Omim: 609131 Human
- SwissProt: O95471 Human
- SwissProt: Q9Z261 Mouse
- SwissProt: Q9Z1L1 Rat
- Unigene: 513915 Human
see all -
別名
- CEPTR L2 antibody
- CEPTRL 2 antibody
- CEPTRL2 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 7 antibody, prediluted (ab27488)Formalin-fixed, paraffin-embedded human colon carcinoma tissue stained for Claudin 7 using ab27488 in immunohistochemical analysis.
参考文献
ab27488 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"