製品の概要

  • 製品名Anti-Claudin 7 antibody
    Claudin 7 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Claudin 7
  • 特異性ab79481 detects endogenous levels of total Claudin 7 protein
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Rat, Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic non phosphopeptide derived from human Claudin 7 around the phosphorylation site of tyrosine 210 (SKEYPV)

  • ポジティブ・コントロール
    • IHC: human prostate carcinoma tissue WB: extracts from rat liver cells

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab79481 was purified by affinity chromatography using an epitope specific immunogen.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab79481 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 23 kDa.
ELISA 1/10000.
IHC-P 1/50 - 1/100.

ターゲット情報

  • 機能Plays a major role in tight junction-specific obliteration of the intercellular space.
  • 組織特異性Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions.
  • 配列類似性Belongs to the claudin family.
  • 翻訳後修飾Phosphorylated.
  • 細胞内局在Cell membrane. Lateral cell membrane. Cell junction > tight junction. Co-localizes with EPCAM at the lateral cell membrane and tight junction.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CEPTR L2 antibody
    • CEPTRL 2 antibody
    • CEPTRL2 antibody
    • Claudin 1 antibody
    • Claudin 9 antibody
    • Claudin-7 antibody
    • Claudin1 antibody
    • Claudin7 antibody
    • Claudin9 antibody
    • CLD7_HUMAN antibody
    • CLDN 7 antibody
    • CLDN-7 antibody
    • CLDN7 antibody
    • Clostridium perfringens enterotoxin receptor like 2 antibody
    • CPETR L2 antibody
    • CPETRL 2 antibody
    • CPETRL2 antibody
    • Hs.84359 antibody
    see all

Anti-Claudin 7 antibody 画像

  • All lanes : Anti-Claudin 7 antibody (ab79481) at 1/500 dilution

    Lane 1 : extracts from rat liver cells
    Lane 2 : extracts from rat liver cells with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 23 kDa
    Observed band size : 31 kDa (why is the actual band size different from the predicted?)
  • Immunohistochemical analysis of Claudin 7 in paraffin embedded human prostate carcinoma tissue, using ab79481 at a 1/100 dilution in the absence (left image) and presence (right image) of the immunizing peptide.

Anti-Claudin 7 antibody (ab79481) 使用論文

ab79481 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab79481.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"