製品の概要

  • 製品名Anti-Claudin 14 antibody
    Claudin 14 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Claudin 14
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Chicken
  • 免疫原

    Synthetic peptide:

    SATHSGYRLNDYV

    conjugated to KLH, corresponding to C terminal amino acids 227-239 of Human Claudin 14 (NP_036262.1).

  • ポジティブ・コントロール
    • Human pancreas tissue; Human liver lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab115868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 26 kDa.
ELISA 1/128000.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
  • 組織特異性Liver, kidney. Also found in ear.
  • 関連疾患Defects in CLDN14 are the cause of deafness autosomal recessive type 29 (DFNB29) [MIM:605608]. DFNB29 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
  • 配列類似性Belongs to the claudin family.
  • 細胞内局在Cell junction > tight junction. Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AI851731 antibody
    • Claudin 14 antibody
    • Claudin-14 antibody
    • CLD14_HUMAN antibody
    • CLDN 14 antibody
    • CLDN14 antibody
    • DFNB 29 antibody
    • DFNB29 antibody
    • Human CLDN14 gene antibody
    • MGC109472 antibody
    • OTTHUMP00000109046 antibody
    • OTTHUMP00000109049 antibody
    • OTTMUSP00000021531 antibody
    • UNQ777/PRO1571 antibody
    see all

Anti-Claudin 14 antibody 画像

  • ab115868, at 5 µg/ml, staining Claudin 14 in Formalin-fixed, Paraffin-embedded Human pancreas tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Anti-Claudin 14 antibody (ab115868) at 1 µg/ml + Human liver lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 26 kDa

Anti-Claudin 14 antibody (ab115868) 使用論文

This product has been referenced in:
  • Gao M  et al. The distinct expression patterns of claudin-10, -14, -17 and E-cadherin between adjacent non-neoplastic tissues and gastric cancer tissues. Diagn Pathol 8:205 (2013). Human . Read more (PubMed: 24325792) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"