Anti-Clathrin heavy chain 抗体 (ab59710)
Key features and details
- Rabbit polyclonal to Clathrin heavy chain
- Suitable for: IHC-P
- Isotype: IgG
製品の概要
-
製品名
Anti-Clathrin heavy chain antibody
Clathrin heavy chain 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Clathrin heavy chain -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差が予測される動物種: Chicken, Cow, Xenopus laevis, Caenorhabditis elegans, Zebrafish, a wide range of other species -
免疫原
Synthetic peptide corresponding to Rat Clathrin heavy chain aa 619-638.
Sequence:KAGLLQRALEHFTDLYDIKR
-
ポジティブ・コントロール
- IHC-P: Non-ciliated bronchiolar cells (Clara cells).
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.02% Thimerosal (merthiolate)
Constituent: Whole serum -
Concentration information loading...
-
精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab59710の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-P |
Use at an assay dependent concentration.
|
特記事項 |
---|
IHC-P
Use at an assay dependent concentration. |
ターゲット情報
-
機能
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. -
配列類似性
Belongs to the clathrin heavy chain family. -
細胞内局在
Cytoplasmic vesicle membrane. Membrane > coated pit. Melanosome. Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. - Information by UniProt
-
参照データベース
- Entrez Gene: 281080 Cow
- Entrez Gene: 323579 Zebrafish
- SwissProt: P49951 Cow
-
別名
- CHC17 antibody
- Clathrin heavy chain antibody
- Clathrin heavy chain 1 antibody
see all
画像
-
ab59710 at 1/1000, overnight, secondary antibody biotinylated goat anti-sheep at 1/3000.
Figure A is a low power image showing intense staining of non-ciliated bronchiolar cells (Clara cells) and lesser staining in alveolar type II cells.
Figure B is a higher power image of the staining of the non ciliated bronchiolar cells.
-
ab59710 at 1/100, overnight, secondary antibody donkey anti-rabbit Cy2® at 1/50. Confocal image shows intense staining of non-ciliated bronchiolar cells (Clara cells).
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (6)
ab59710 は 6 報の論文で使用されています。
- Ríos H et al. The role of PDLIM1, a PDZ-LIM domain protein, at the ribbon synapses in the chicken retina. J Comp Neurol 528:1820-1832 (2020). PubMed: 31930728
- Fu W et al. 17ß-Estradiol Inhibits PCSK9-Mediated LDLR Degradation Through GPER/PLC Activation in HepG2 Cells. Front Endocrinol (Lausanne) 10:930 (2019). PubMed: 32082252
- Eno C et al. aura (mid1ip1l) regulates the cytoskeleton at the zebrafish egg-to-embryo transition. Development 143:1585-99 (2016). PubMed: 26965374
- Garcin PO & Panté N Cell migration is another player of the minute virus of mice infection. Virology 468-470C:150-159 (2014). Mouse . PubMed: 25173091
- Fowler R et al. Uptake and transport of B12-conjugated nanoparticles in airway epithelium. J Control Release 172:374-81 (2013). ICC/IF ; Human . PubMed: 24008152
- Wahl S et al. A local, periactive zone endocytic machinery at photoreceptor synapses in close vicinity to synaptic ribbons. J Neurosci 33:10278-300 (2013). PubMed: 23785143