製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to cIAP2
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Rat
    交差が予測される動物種: Human
  • 免疫原

    Synthetic peptide:

    C-SVNNLEATSQP

    , corresponding to internal sequence amino acids 101-111 of Human cIAP2 according to NP_001156.1

  • ポジティブ・コントロール
    • Rat testis lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab109549 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 67 kDa.

ターゲット情報

  • 機能
    Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).
  • 組織特異性
    Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes.
  • 関連疾患
    Note=A chromosomal aberration involving BIRC3 is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma). Translocation t(11;18)(q21;q21) with MALT1. This translocation is found in approximately 50% of cytogenetically abnormal low-grade MALT lymphoma.
  • 配列類似性
    Belongs to the IAP family.
    Contains 3 BIR repeats.
    Contains 1 CARD domain.
    Contains 1 RING-type zinc finger.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AIP 1 antibody
    • AIP1 antibody
    • API 2 antibody
    • API2 antibody
    • Apoptosis inhibitor 2 antibody
    • Baculoviral IAP repeat containing 3 antibody
    • Baculoviral IAP repeat containing protein 3 antibody
    • Baculoviral IAP repeat-containing protein 3 antibody
    • BIRC 3 antibody
    • BIRC3 antibody
    • BIRC3_HUMAN antibody
    • C IAP2 antibody
    • C-IAP2 antibody
    • CIAP 2 antibody
    • CIAP2 antibody
    • HAIP 1 antibody
    • HAIP1 antibody
    • HIAP 1 antibody
    • HIAP-1 antibody
    • HIAP1 antibody
    • IAP homolog C antibody
    • IAP-1 antibody
    • Inhibitor of apoptosis protein 1 antibody
    • MALT 2 antibody
    • MALT2 antibody
    • Mammalian IAP homolog C antibody
    • MIHC antibody
    • RING finger protein 49 antibody
    • RNF49 antibody
    • TNFR2 TRAF signaling complex protein 1 antibody
    • TNFR2 TRAF signalling complex protein antibody
    • TNFR2-TRAF-signaling complex protein 1 antibody
    see all

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プロトコール

参考文献

ab109549 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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