Anti-cIAP2 抗体 (ab109549)
Key features and details
- Goat polyclonal to cIAP2
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-cIAP2 antibody
cIAP2 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to cIAP2 -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat
交差が予測される動物種: Human -
免疫原
Synthetic peptide:
C-SVNNLEATSQP
, corresponding to internal sequence amino acids 101-111 of Human cIAP2 according to NP_001156.1 -
ポジティブ・コントロール
- Rat testis lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.05% Tris buffered saline, 0.5% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab109549の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 67 kDa.
1 hour primary incubation is recommended for this product. |
特記事項 |
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WB
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 67 kDa. 1 hour primary incubation is recommended for this product. |
ターゲット情報
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機能
Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). -
組織特異性
Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes. -
関連疾患
Note=A chromosomal aberration involving BIRC3 is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma). Translocation t(11;18)(q21;q21) with MALT1. This translocation is found in approximately 50% of cytogenetically abnormal low-grade MALT lymphoma. -
配列類似性
Belongs to the IAP family.
Contains 3 BIR repeats.
Contains 1 CARD domain.
Contains 1 RING-type zinc finger. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 330 Human
- Entrez Gene: 78971 Rat
- Omim: 601721 Human
- SwissProt: Q13489 Human
- Unigene: 127799 Human
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別名
- AIP 1 antibody
- AIP1 antibody
- API 2 antibody
see all
画像
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Anti-cIAP2 antibody (ab109549) at 1 µg/ml + Rat testis lysate at 35 µg
Predicted band size: 67 kDa
Observed band size: 52,70 kDa why is the actual band size different from the predicted?
データシートおよび資料
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Datasheet download
参考文献 (0)
ab109549 は論文での使用が確認できていません。