Anti-cIAP1 抗体 - N-terminal (ab196592)
Key features and details
- Rabbit polyclonal to cIAP1 - N-terminal
- Suitable for: IHC-P, WB, ICC/IF
- Reacts with: Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-cIAP1 antibody - N-terminal
cIAP1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to cIAP1 - N-terminal -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, WB, ICC/IFmore details -
種交差性
交差種: Rat, Human -
免疫原
Recombinant fragment corresponding to Human cIAP1 (N terminal).
Database link: Q13490 -
ポジティブ・コントロール
- Jurkat, HeLa and HT29 cell extract. Rat kidney tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 0.87% Sodium chloride, 50% Glycerol (glycerin, glycerine)
without Mg2+ and Ca2+ -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab196592の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-P |
1/50 - 1/200.
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|
WB |
1/500 - 1/2000. Predicted molecular weight: 70 kDa.
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|
ICC/IF |
1/50 - 1/200.
|
特記事項 |
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IHC-P
1/50 - 1/200. |
WB
1/500 - 1/2000. Predicted molecular weight: 70 kDa. |
ICC/IF
1/50 - 1/200. |
ターゲット情報
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機能
Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). -
組織特異性
Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes. -
配列類似性
Belongs to the IAP family.
Contains 3 BIR repeats.
Contains 1 CARD domain.
Contains 1 RING-type zinc finger. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 329 Human
- Entrez Gene: 60371 Rat
- Omim: 601712 Human
- SwissProt: Q13490 Human
- Unigene: 696238 Human
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別名
- API 1 antibody
- API1 antibody
- Apoptosis inhibitor 1 antibody
see all
画像
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All lanes : Anti-cIAP1 antibody - N-terminal (ab196592) at 1/500 dilution
Lane 1 : Jurkat cell extract
Lane 2 : HeLa cell extract
Lane 3 : HT29 cell extract
Predicted band size: 70 kDa -
Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue labeling cIAP1 using ab196592 at a 1/200 dilution.
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Immunohistochemical analysis of paraffin-embedded rat kidney tissue labeling cIAP1 using ab196592 at a 1/200 dilution.
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Immunofluorescence analysis of A549 cells labeling cIAP1 using ab195692 at a 1/50 dilution.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab196592 は 1 報の論文で使用されています。
- Zhu DL & Shuai LY Effects of Birinapant on Proliferation and Invasion of MGC-803 Gastric Cancer Cells and Mechanism Underlying These Effects. Bull Exp Biol Med 171:56-61 (2021). PubMed: 34050412