製品の概要

  • 製品名Anti-CHX10 antibody
    CHX10 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CHX10
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 250 - 350 of Human CHX10.

  • ポジティブ・コントロール
    • This antibody gave a positive signal in Human liver tissue lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab93715 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).

ターゲット情報

  • 機能Plays a significant role in the specification and morphogenesis of the sensory retina. May also participate in the development of the cells of the inner nuclear layer, particularly bipolar cells.
  • 組織特異性Abundantly expressed in retinal neuroblasts during eye development and in the inner nuclear layer of the adult retina. Within this layer, expression is stronger in the outer margin where bipolar cells predominate.
  • 関連疾患Defects in VSX2 are the cause of microphthalmia isolated type 2 (MCOP2) [MIM:610093]; also known as isolated clinical anophthalmia. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, cataractand other abnormalities like cataract may also be present.
    Defects in VSX2 are the cause of microphthalmia with cataracts and iris abnormalities (MCOPCTI) [MIM:610092].
    Defects in VSX2 are the cause of microphthalmia isolated with coloboma type 3 (MCOPCB3) [MIM:610092]; also known as isolated colobomatous microphthalmia 3. Ocular colobomas are a set of malformations resulting from abnormal morphogenesis of the optic cup and stalk, and the fusion of the fetal fissure (optic fissure).
  • 配列類似性Belongs to the paired homeobox family.
    Contains 1 CVC domain.
    Contains 1 homeobox DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C elegans ceh 10 homeo domain containing homolog antibody
    • Ceh 10 homeo domain containing homolog (C. elegans) antibody
    • Ceh 10 homeo domain containing homolog antibody
    • Ceh 10 homeodomain containing homolog antibody
    • Ceh 10 homeodomain containing homolog (C. elegans) antibody
    • Ceh-10 homeodomain-containing homolog antibody
    • Ceh10 homeo domain containing homolog antibody
    • Ceh10 homeodomain containing homolog antibody
    • CHX 10 antibody
    • Homeobox protein CHX 10 antibody
    • Homeobox protein CHX10 antibody
    • HOX 10 antibody
    • HOX10 antibody
    • MCOP 2 antibody
    • MCOP2 antibody
    • MCOPCB 3 antibody
    • MCOPCB3 antibody
    • RET 1 antibody
    • RET1 antibody
    • Visual system homeobox 2 antibody
    • Vsx 2 antibody
    • Vsx2 antibody
    • VSX2_HUMAN antibody
    see all

Anti-CHX10 antibody 画像

  • Anti-CHX10 antibody (ab93715) at 1 µg/ml + Human liver tissue lysate - total protein (ab29889) at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 39 kDa
    Observed band size : 39 kDa
    Additional bands at : 61 kDa,71 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 4 minutes

Anti-CHX10 antibody (ab93715) 使用論文

ab93715 has not yet been referenced specifically in any publications.

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