製品の概要

  • 製品名Anti-CHST3 antibody
    CHST3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CHST3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 32-62 of Human CHST3 (NP_004264.2)

  • ポジティブ・コントロール
    • Mouse spleen tissue lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab107093 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 55 kDa.

ターゲット情報

  • 機能Catalyzes the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues of keratan sulfate, another glycosaminoglycan, and the Gal residues in sialyl N-acetyllactosamine (sialyl LacNAc) oligosaccharides. May play a role in the maintenance of naive T-lymphocytes in the spleen.
  • 組織特異性Widely expressed in adult tissues. Expressed in heart, placenta, skeletal muscle and pancreas. Also expressed in various immune tissues such as spleen, lymph node, thymus and appendix.
  • 関連疾患Defects in CHST3 are a cause of spondyloepiphyseal dysplasia with congenital joint dislocations (SEDC-JD) [MIM:143095]. A bone dysplasia clinically characterized by dislocation of the knees and/or hips at birth, clubfoot, elbow joint dysplasia with subluxation and limited extension, short stature, and progressive kyphosis developing in late childhood. The disorder is usually evident at birth, with short stature and multiple joint dislocations or subluxations that dominate the neonatal clinical and radiographic picture. During childhood, the dislocations improve, both spontaneously and with surgical treatment, and features of spondyloepiphyseal dysplasia become apparent, leading to arthritis of the hips and spine with intervertebral disk degeneration, rigid kyphoscoliosis, and trunk shortening by late childhood.
  • 配列類似性Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
  • 細胞内局在Golgi apparatus membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C6ST 1 antibody
    • C6ST antibody
    • C6ST-1 antibody
    • C6ST1 antibody
    • Carbohydrate (chondroitin 6) sulfotransferase 3 antibody
    • Carbohydrate sulfotransferase 3 antibody
    • Chondroitin 6 O sulfotransferase 1 antibody
    • Chondroitin 6 sulfotransferase antibody
    • Chondroitin 6-O-sulfotransferase 1 antibody
    • Chondroitin 6-sulfotransferase antibody
    • CHST 3 antibody
    • Chst3 antibody
    • CHST3_HUMAN antibody
    • Galactose/N acetylglucosamine/N acetylglucosamine 6 O sulfotransferase 0 antibody
    • Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0 antibody
    • GST 0 antibody
    • GST-0 antibody
    • GST0 antibody
    see all

Anti-CHST3 antibody 画像

  • Anti-CHST3 antibody (ab107093) at 1/100 dilution + Mouse spleen tissue lysate at 35 µg

    Predicted band size : 55 kDa

Anti-CHST3 antibody (ab107093) 使用論文

ab107093 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"