製品の概要

  • 製品名Anti-CHST14 antibody
  • 製品の詳細
    Rabbit polyclonal to CHST14
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 177-205 of Human CHST14 (NP_569735.1).

  • ポジティブ・コントロール
    • Mouse stomach tissue lysates.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファーPreservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab116308 is purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノポリクローナル
  • アイソタイプIgG

アプリケーション

Our Abpromise guarantee covers the use of ab116308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 43 kDa.

ターゲット情報

  • 機能Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA.
  • 組織特異性Widely expressed. Expressed at high level in pituitary gland, placenta, uterus and thyroid.
  • 関連疾患Defects in CHST14 are the cause of Ehlers-Danlos syndrome musculocontractural type (EDSMC) [MIM:601776]. It is a form of Ehlers-Danlos syndrome characterized by distinctive craniofacial dysmorphism, congenital contractures of thumbs and fingers, clubfeet, severe kyphoscoliosis, muscular hypotonia, hyperextensible thin skin with easy bruisability and atrophic scarring, wrinkled palms, joint hypermobility, and ocular involvement.
  • 配列類似性Belongs to the sulfotransferase 2 family.
  • 細胞内局在Golgi apparatus membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 2600016L03Rik antibody
    • ATCS antibody
    • Carbohydrate (N acetylgalactosamine 4 0) sulfotransferase 14 antibody
    • Carbohydrate sulfotransferase 14 antibody
    • CHST14 antibody
    • CHSTE_HUMAN antibody
    • D4ST-1 antibody
    • D4st1 antibody
    • Dermatan 4-sulfotransferase 1 antibody
    • hD4ST1 antibody
    • RP23-286G12.2 antibody
    • UNQ1925/PRO4400 antibody
    see all

Anti-CHST14 antibody 画像

  • Anti-CHST14 antibody (ab116308) at 1/100 dilution + Mouse stomach tissue lysates at 15 µg

    Predicted band size : 43 kDa

Anti-CHST14 antibody (ab116308) 使用論文

ab116308 has not yet been referenced specifically in any publications.

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