製品の概要

  • 製品名
    Anti-CHREBP antibody - ChIP Grade
    CHREBP 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CHREBP - ChIP Grade
  • アプリケーション
    適用あり: IHC-P, WB, ICC/IF, ChIPmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide, corresponding to C terminal amino acids 800-852 of Human CHREBP

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab92809 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
WB
ICC/IF
ChIP
  • 追加情報
    ChIP: Use at an assay dependent dilution.
    ICC/IF: 1/100 - 1/500.
    IHC-P: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 95 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3'.
    • 組織特異性
      Expressed in liver, heart, kidney, cerebellum and intestinal tissues.
    • 関連疾患
      Note=WBSCR14 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of WBSCR14 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
    • 配列類似性
      Contains 1 basic helix-loop-helix (bHLH) domain.
    • 細胞内局在
      Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • carbohydrate response element binding protein antibody
      • bHLHd14 antibody
      • Carbohydrate responsive element binding protein antibody
      • Class D basic helix-loop-helix protein 14 antibody
      • MIO antibody
      • MLX interacting protein like antibody
      • Mlx interactor antibody
      • MLX-interacting protein-like antibody
      • MLXIPL antibody
      • MONDOB antibody
      • WBS14_HUMAN antibody
      • WBSCR 14 antibody
      • WBSCR14 antibody
      • Williams Beuren syndrome chromosome region 14 antibody
      • Williams Beuren syndrome chromosome region 14 protein antibody
      • Williams-Beuren syndrome chromosomal region 14 protein antibody
      • WS basic helix loop helix leucine zipper protein antibody
      • WS basic-helix-loop-helix leucine zipper protein antibody
      • WS bHLH antibody
      • WS-bHLH antibody
      see all

    画像

    • anti CHREBP staining CHREBP in human hepatocyte by Immunofluorescence. Overlay staining of ChREBP (rhodamine red) and DAPI nuclear staining (blue).
    • anti CHREBP staining CHREBP in colon epithelium (40X) by immunohistochemistry.
    • Anti-CHREBP antibody - ChIP Grade (ab92809) (anti CHREBP) + humna hepatocyte lysate at 20 µg

      Predicted band size : 95 kDa

    参考文献

    This product has been referenced in:
    • Zhang Y  et al. Berberine reverses abnormal expression of L-type pyruvate kinase by DNA demethylation and histone acetylation in the livers of the non-alcoholic fatty disease rat. Int J Clin Exp Med 8:7535-43 (2015). Read more (PubMed: 26221297) »
    • Erion DM  et al. The role of the carbohydrate response element-binding protein in male fructose-fed rats. Endocrinology 154:36-44 (2013). WB . Read more (PubMed: 23161873) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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