Anti-Cholecystokinin 8 抗体 [27F3..0,5D10] (ab37274)
Key features and details
- Mouse monoclonal [27F3..0,5D10] to Cholecystokinin 8
- Suitable for: IHC-FoFr, ELISA
- Reacts with: Rat
- Isotype: IgG2a
製品の概要
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製品名
Anti-Cholecystokinin 8 antibody [27F3..0,5D10] -
製品の詳細
Mouse monoclonal [27F3..0,5D10] to Cholecystokinin 8 -
由来種
Mouse -
特異性
Reacts with CCK-8 and the other CCK analogs with identical C-terminal ends as well as Gastrin 17. No reactivity was observed with Human Heparin cofactor II. -
アプリケーション
適用あり: IHC-FoFr, ELISAmore details -
種交差性
交差種: Rat -
免疫原
CCK-8 fragment 26-33 GGDRDY(SO3H)MGWMDF
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. -
バッファー
pH: 7.40
Constituents: 2.9% Sodium chloride, 0.0268% PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
27F3..0,5D10 -
ミエローマ
x63-Ag8.653 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab37274の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-FoFr |
Use at an assay dependent concentration. PubMed: 22892424
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ELISA |
Use at an assay dependent concentration.
We recommend coating with CCK-8 and using the antibody in a competitive assay protocol. Increased reactivity with sulphated CCK-8 compared to non-sulphated CCK-8 has been observed. |
特記事項 |
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IHC-FoFr
Use at an assay dependent concentration. PubMed: 22892424 |
ELISA
Use at an assay dependent concentration. We recommend coating with CCK-8 and using the antibody in a competitive assay protocol. Increased reactivity with sulphated CCK-8 compared to non-sulphated CCK-8 has been observed. |
ターゲット情報
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細胞内局在
Secreted -
参照データベース
- Entrez Gene: 25298 Rat
- SwissProt: P01355 Rat
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別名
- CCK antibody
- CCK8 antibody
- Cholecystokinin 8 antibody
- Cholecystokinin antibody
データシートおよび資料
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Datasheet download
参考文献 (10)
ab37274 は 10 報の論文で使用されています。
- Rice HC et al. Contribution of GABAergic interneurons to amyloid-ß plaque pathology in an APP knock-in mouse model. Mol Neurodegener 15:3 (2020). PubMed: 31915042
- Boccalaro IL et al. Dopamine depletion induces neuron-specific alterations of GABAergic transmission in the mouse striatum. Eur J Neurosci 52:3353-3374 (2020). PubMed: 32599671
- Bülbül M et al. Acute restraint stress induces cholecystokinin release via enteric apelin. Neuropeptides 73:71-77 (2019). PubMed: 30503693
- Modi B et al. Possible Implication of the CA2 Hippocampal Circuit in Social Cognition Deficits Observed in the Neuroligin 3 Knock-Out Mouse, a Non-Syndromic Animal Model of Autism. Front Psychiatry 10:513 (2019). PubMed: 31379628
- Bülbül M et al. Central apelin administration and restraint stress induce hypothalamic cholecystokinin release via the APJ receptor. J Neuroendocrinol 30:e12635 (2018). PubMed: 30044523
- Packard AEB et al. Sucrose-induced plasticity in the basolateral amygdala in a 'comfort' feeding paradigm. Brain Struct Funct 222:4035-4050 (2017). PubMed: 28597100
- Harden SW & Frazier CJ Oxytocin depolarizes fast-spiking hilar interneurons and induces GABA release onto mossy cells of the rat dentate gyrus. Hippocampus 26:1124-39 (2016). PubMed: 27068005
- Früh S et al. Neuronal Dystroglycan Is Necessary for Formation and Maintenance of Functional CCK-Positive Basket Cell Terminals on Pyramidal Cells. J Neurosci 36:10296-10313 (2016). IHC ; Mouse . PubMed: 27707967
- Iijima T et al. Neuronal cell type-specific alternative splicing is regulated by the KH domain protein SLM1. J Cell Biol 204:331-42 (2014). PubMed: 24469635
- Thibault K et al. Activation-Dependent Subcellular Distribution Patterns of CB1 Cannabinoid Receptors in the Rat Forebrain. Cereb Cortex : (2012). WB ; Rat . PubMed: 22892424