製品の概要

  • 製品名Anti-CHN 1 antibody
    CHN 1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to CHN 1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 91-201 of Human CHN 1

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab54610 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能GTPase-activating protein for p21-rac and a phorbol ester receptor. May play an important role in neuronal signal-transduction mechanisms.
    • 組織特異性In neurons in brain regions that are involved in learning and memory processes.
    • 関連疾患Defects in CHN1 are the cause of Duane retraction syndrome type 2 (DURS2) [MIM:604356]. Duane retraction syndrome is a congenital eye movement disorder characterized by a failure of cranial nerve VI (the abducens nerve) to develop normally, resulting in restriction or absence of abduction, adduction, or both, and narrowing of the palpebral fissure and retraction of the globe on attempted adduction. Undiagnosed in children, it can lead to amblyopia, a permanent uncorrectable loss of vision.
    • 配列類似性Contains 1 phorbol-ester/DAG-type zinc finger.
      Contains 1 Rho-GAP domain.
      Contains 1 SH2 domain.
    • 発生段階Increases in amount during brain development coincident with synaptogenesis.
    • Information by UniProt
    • 参照データベース
    • 別名
      • A-chimaerin antibody
      • Alpha-chimerin antibody
      • ARHGAP2 antibody
      • CHIN_HUMAN antibody
      • CHN antibody
      • Chn1 antibody
      • N chimaerin antibody
      • N chimerin antibody
      • N-chimaerin antibody
      • N-chimerin antibody
      • NC antibody
      • Rho GTPase-activating protein 2 antibody
      • RHOGAP2 antibody
      see all

    Anti-CHN 1 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab54610 CHN 1 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-CHN 1 antibody (ab54610) 使用論文

    ab54610 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab54610.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"