製品の概要

  • 製品名Anti-CHMP4A antibody
    CHMP4A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CHMP4A
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Rabbit
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 210-259 (ELEQEELAQE LLNVGDKEEE PSVKLPSVPS THLPAGPAPK VDEDEEALKQ) of Human CHMP4A (NP_054888).

  • ポジティブ・コントロール
    • 721_B cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーConstituents: 98% PBS, 2% Sucrose
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab116340 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 関連性Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In the ESCRT-III complex, it probably serves as an acceptor for ESCRT-I complex on endosomal membranes. In case of infection, the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargos of viral proteins, via the association of CHMP4 proteins with PDCD6IP/AIP1, a protein directly recruited by HIV-1 p6 protein that functions at sites of viral Gag assembly and budding.
  • 細胞内局在Cytoplasmic: Cytoplasmic vesicle membrane. Membrane-associated - localizes to large vesicle-like structures.
  • 参照データベース
  • 別名
    • C14orf123 antibody
    • Charged multivesicular body protein 4a antibody
    • Chromatin modifying protein 4a antibody
    • HSPC134 antibody
    • SHAX2 antibody
    see all

Anti-CHMP4A antibody 画像

  • Anti-CHMP4A antibody (ab116340) at 1 µg/ml + 721_B cell lysate at 10 µg

    Predicted band size : 25 kDa

Anti-CHMP4A antibody (ab116340) 使用論文

ab116340 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab116340.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"