Anti-FOXN3 抗体 [CHESC9H4] (ab50756)
Key features and details
- Mouse monoclonal [CHESC9H4] to FOXN3
- Suitable for: Dot blot, WB
- Reacts with: Recombinant fragment
- Isotype: IgG1
製品の概要
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製品名
Anti-FOXN3 antibody [CHESC9H4]
FOXN3 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [CHESC9H4] to FOXN3 -
由来種
Mouse -
アプリケーション
適用あり: Dot blot, WBmore details -
種交差性
交差種: Recombinant fragment
交差が予測される動物種: Human -
免疫原
Recombinant fragment corresponding to FOXN3.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C. -
バッファー
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 1% BSA, PBS -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
Purified using protein G column chromatography from culture supernatant of hybridoma cultured in a meium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. Filtered through a 0.22 micrometer membrane. -
ポリ/モノ
モノクローナル -
クローン名
CHESC9H4 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab50756の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Dot blot |
Use at an assay dependent concentration.
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WB | (2) |
Use at an assay dependent concentration.
|
特記事項 |
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Dot blot
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints). -
配列類似性
Contains 1 fork-head DNA-binding domain. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 1112 Human
- Omim: 602628 Human
- SwissProt: O00409 Human
- Unigene: 434286 Human
- Unigene: 621371 Human
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別名
- C14orf116 antibody
- Checkpoint suppressor 1 antibody
- CHES1 antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (3)
ab50756 は 3 報の論文で使用されています。
- Xue W et al. FOXN3 is downregulated in osteosarcoma and transcriptionally regulates SIRT6, and suppresses migration and invasion in osteosarcoma. Oncol Rep 41:1404-1414 (2019). PubMed: 30483801
- Sun J et al. The transcription factor FOXN3 inhibits cell proliferation by downregulating E2F5 expression in hepatocellular carcinoma cells. Oncotarget 7:43534-43545 (2016). WB . PubMed: 27259277
- Huot G et al. CHES1/FOXN3 regulates cell proliferation by repressing PIM2 and protein biosynthesis. Mol Biol Cell 25:554-65 (2014). PubMed: 24403608