製品の概要

  • 製品名Anti-CHCHD3 antibody
    CHCHD3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CHCHD3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Sheep, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 35-84 (RMKESSPSGS KSQRYSGAYG ASVSDEELKR RVAEELALEQ AKKESEDQKR) of Human CHCHD3 (NP_060282).

  • ポジティブ・コントロール
    • Hela cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab98975 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 26 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Required for maintenance of mitochondrial crista integrity and mitochondrial function. May act as a scaffolding protein that stabilizes protein complexes involved in crista architecture and protein import. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription.
  • 組織特異性Detected at low levels in brain, placenta, lung, liver, kidney and pancreas with increased levels in heart and skeletal muscle. Higher expression in primary lung cancers than in normal lung tissue.
  • 配列類似性Contains 1 CHCH domain.
  • 細胞内局在Mitochondrion inner membrane. Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CHCH3_HUMAN antibody
    • CHCHD 3 antibody
    • Chchd3 antibody
    • Coiled coil helix coiled coil helix domain containing 3 antibody
    • Coiled coil helix coiled coil helix domain containing protein 3 mitochondrial antibody
    • Coiled-coil-helix-coiled-coil-helix domain-containing protein 3 antibody
    • FLJ20420 antibody
    • MINOS3 antibody
    • mitochondrial antibody
    • Mitochondrial inner membrane organizing system 3 antibody
    • PPP1R22 antibody
    • Protein phosphatase 1 regulatory subunit 22 antibody
    see all

Anti-CHCHD3 antibody 画像

  • Anti-CHCHD3 antibody (ab98975) at 1 µg/ml + Hela cell lysate at 10 µg

    Predicted band size : 26 kDa

Anti-CHCHD3 antibody (ab98975) 使用論文

This product has been referenced in:
  • Ott C  et al. Sam50 functions in mitochondrial intermembrane space bridging and biogenesis of respiratory complexes. Mol Cell Biol 32:1173-88 (2012). WB . Read more (PubMed: 22252321) »
  • Darshi M  et al. Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space. J Biol Chem 287:39480-91 (2012). WB ; Human . Read more (PubMed: 23019327) »

See all 2 Publications for this product

Product Wall

Thank you for contacting us.

Regarding antibodies ab79397 and ab32577, they both have been tested in IHC with paraffin embedded sections in the species stated on the datasheet. We don’t have preliminary data using them with frozen secti...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"