The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed.
Calcitonin/calcitonin related polypeptide alpha antibody
Alpha type CGRP antibody
Beta type CGRP antibody
Calcitonin 1 antibody
Calcitonin 2 antibody
Calcitonin gene related peptide I antibody
Calcitonin gene related peptide II antibody
Calcitonin related polypeptide alpha antibody
Calcitonin related polypeptide beta antibody
CGRP I antibody
CGRP II antibody
This product has been referenced in:
Garratt LW et al. Matrix metalloproteinase activation by free neutrophil elastase contributes to bronchiectasis progression in early cystic fibrosis. Eur Respir J46:384-94 (2015).
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