製品の概要

  • 製品名Anti-CGRP antibody
    CGRP 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to CGRP
  • 特異性There were no cross reactivities obtained with human and salmon Katacalcin and Calcitonin
  • アプリケーション適用あり: RIAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    ACNTATCVTHRLAGLLSRSGGMVKSNFVPTNVGSKAF

    , corresponding to C terminal amino acids 82-118 of Human CGRP.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab14180 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
RIA 1/3000.

ターゲット情報

  • 関連性CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed.
  • 細胞内局在Endoplasmic reticulum and Secreted
  • 参照データベース
  • 別名
    • Calcitonin/calcitonin related polypeptide alpha antibody
    • Alpha type CGRP antibody
    • Beta type CGRP antibody
    • CALC1 antibody
    • CALC2 antibody
    • CALCA antibody
    • CALCB antibody
    • Calcitonin 1 antibody
    • Calcitonin 2 antibody
    • Calcitonin gene related peptide I antibody
    • Calcitonin gene related peptide II antibody
    • Calcitonin related polypeptide alpha antibody
    • Calcitonin related polypeptide beta antibody
    • CGRP antibody
    • CGRP I antibody
    • CGRP II antibody
    • CGRP1 antibody
    • CGRP2 antibody
    • CT antibody
    • Katacalcin antibody
    • KC antibody
    see all

Anti-CGRP antibody (ab14180) 使用論文

This product has been referenced in:
  • Garratt LW  et al. Matrix metalloproteinase activation by free neutrophil elastase contributes to bronchiectasis progression in early cystic fibrosis. Eur Respir J 46:384-94 (2015). Read more (PubMed: 25929954) »

See 1 Publication for this product

Product Wall

Thank you for contacting us. We have several antibodies capable of detecting both alpha and beta CGRP, but none appear likely to be able to distinguish between alpha and beta, judging from the immunogens they are raised against. The immunogens ...

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Thank you for your enquiry. I have examined each of the antibodies against one another with respect to your application of ICC in murine cells. ab10987 is a monoclonal antiserum that recognizes 10 amino acids in the C-terminus and recognizes hu...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"