製品の概要

  • 製品名
    CGP 37849
  • 製品の詳細
    Competitive NMDA antagonist
  • 生理活性の詳細
    Competitive NMDA receptor antagonist (Ki = 35 nM for displacement of CPP binding in rat brain). Potent oral anticonvulsant activity in vivo.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Fagg GE  et al. CGP 37849 and CGP 39551: novel and potent competitive N-methyl-D-aspartate receptor antagonists with oral activity. Br J Pharmacol 99:791-7 (1990). Read more (PubMed: 1972895) »
  • Schmutz M  et al. The competitive NMDA receptor antagonists CGP 37849 and CGP 39551 are potent, orally-active anticonvulsants in rodents. Naunyn Schmiedebergs Arch Pharmacol 342:61-6 (1990). Read more (PubMed: 1976233) »
  • Fagg GE  et al. CGP 37849 and CGP 39551: novel competitive N-methyl-D-aspartate receptor antagonists with potent oral anticonvulsant activity. Prog Clin Biol Res 361:421-7 (1990). Read more (PubMed: 1981260) »

See all 2 Publications for this product

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