製品の概要

  • 製品名Anti-CFHR5 antibody
    CFHR5 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CFHR5
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-569 of Human CFHR5 (NP_110414.1).

  • ポジティブ・コントロール
    • CFHR5 transfected 293T cell line.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab118122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 64 kDa.
IP Use at an assay dependent dilution.

ターゲット情報

  • 機能Involved in complement regulation.
  • 組織特異性Expressed by the liver and secreted in plasma.
  • 関連疾患Note=Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. Atypical hemolytic uremic syndrome is a complex genetic disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure and absence of episodes of enterocolitis and diarrhea. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease. Susceptibility to the development of atypical hemolytic uremic syndrome can be conferred by mutations in various components of or regulatory factors in the complement cascade system. Other genes may play a role in modifying the phenotype.
  • 配列類似性Contains 9 Sushi (CCP/SCR) domains.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CFHL5 antibody
    • CFHR5 antibody
    • CFHR5D antibody
    • Complement factor H-related 5 antibody
    • Complement factor H-related protein 5 antibody
    • factor H-related gene 5 antibody
    • factor H-related protein 5 antibody
    • FHR-5 antibody
    • FHR5 antibody
    • FHR5_HUMAN antibody
    • FLJ10549 antibody
    • MGC133240 antibody
    • OTTHUMP00000034672 antibody
    see all

Anti-CFHR5 antibody 画像

  • All lanes : Anti-CFHR5 antibody (ab118122) at 1/1000 dilution

    Lane 1 : 293T cell line, transfected with CFHR5
    Lane 2 : 293T cell line, non-transfected

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 64 kDa
  • Immunoprecipitation of CFHR5 transfected lysate using ab118122 antibody and Protein A Magnetic Beads, immunoblotted with ab118122.

Anti-CFHR5 antibody (ab118122) 使用論文

ab118122 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"