Anti-CETP 抗体 (ab19012)
Key features and details
- Rabbit polyclonal to CETP
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-CETP antibody
CETP 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to CETP -
由来種
Rabbit -
特異性
This antibody recognises CETB (70 kDa). -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human CETP (N terminal). Immunogen is around amino acid 153.
Database link: P11597 -
ポジティブ・コントロール
- WB: Jurkat cell lysate
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特記事項
This product is manufactured by BioVision, an Abcam company and was previously called 3413 CETP Antibody. 3413-100 is the same size as the 100 µg size of ab19012.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA -
Concentration information loading...
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ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab19012の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 0.5 - 4 µg/ml. Predicted molecular weight: 70 kDa.
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特記事項 |
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WB
Use a concentration of 0.5 - 4 µg/ml. Predicted molecular weight: 70 kDa. |
ターゲット情報
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機能
Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol. -
組織特異性
Expressed by the liver and secreted in plasma. -
関連疾患
Defects in CETP are a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
Defects in CETP are the cause of cholesteryl ester transfer protein deficiency (CETP deficiency) [MIM:607322]. This is an autosomal dominant condition associated with increased HDL cholesterol levels. -
配列類似性
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. -
細胞内局在
Secreted > extracellular space. - Information by UniProt
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参照データベース
- Entrez Gene: 1071 Human
- Omim: 118470 Human
- SwissProt: P11597 Human
- Unigene: 89538 Human
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別名
- BPIFF antibody
- CETP antibody
- CETP_HUMAN antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab19012 は 5 報の論文で使用されています。
- Cho KH et al. Consumption of Cuban Policosanol Improves Blood Pressure and Lipid Profile via Enhancement of HDL Functionality in Healthy Women Subjects: Randomized, Double-Blinded, and Placebo-Controlled Study. Oxid Med Cell Longev 2018:4809525 (2018). PubMed: 29854085
- Park KH et al. Slim Body Weight Is Highly Associated With Enhanced Lipoprotein Functionality, Higher HDL-C, and Large HDL Particle Size in Young Women. Front Endocrinol (Lausanne) 9:406 (2018). PubMed: 30072955
- Kim JY et al. Patients with Rheumatoid Arthritis Show Altered Lipoprotein Profiles with Dysfunctional High-Density Lipoproteins that Can Exacerbate Inflammatory and Atherogenic Process. PLoS One 11:e0164564 (2016). ELISA ; Human . PubMed: 27736980
- Park J et al. Females with angina pectoris have altered lipoprotein metabolism with elevated cholesteryl ester transfer protein activity and impaired high-density lipoproteins-associated antioxidant enzymes. Int J Mol Med 29:683-9 (2012). WB . PubMed: 22211242
- Cho KH et al. Myocardial infarction patients show altered lipoprotein properties and functions when compared with stable angina pectoris patients. Exp Mol Med 41:67-76 (2009). ELISA ; Human . PubMed: 19287187