製品の概要

  • 製品名Anti-Ceruloplasmin antibody
    Ceruloplasmin 一次抗体 製品一覧
  • 製品の詳細
    Chicken polyclonal to Ceruloplasmin
  • アプリケーション適用あり: WB, ELISA, more details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length native protein: highly purified human ceruloplasmin isolated from human serum

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgY
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab47785 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
Depletion
  • 追加情報Depletion: Use at an assay dependent dilution.
    ELISA: 1/200 - 1/500.
    WB: 1/1000. Predicted molecular weight: 122 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane.
    • 組織特異性Expressed by the liver and secreted in plasma.
    • 関連疾患Defects in CP are the cause of aceruloplasminemia (ACERULOP) [MIM:604290]. It is an autosomal recessive disorder of iron metabolism characterized by iron accumulation in the brain as well as visceral organs. Clinical features consist of the triad of retinal degeneration, diabetes mellitus and neurological disturbances.
      Note=Ceruloplasmin levels are decreased in Wilson disease, in which copper cannot be incorporated into ceruloplasmin in liver because of defects in the copper-transporting ATPase 2.
    • 配列類似性Belongs to the multicopper oxidase family.
      Contains 3 F5/8 type A domains.
      Contains 6 plastocyanin-like domains.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CERU_HUMAN antibody
      • Ceruloplasmin antibody
      • CP 2 antibody
      • CP antibody
      • CP2 antibody
      • Ferroxidase antibody
      see all

    Anti-Ceruloplasmin antibody (ab47785) 使用論文

    ab47785 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab47785.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"