製品の概要

  • 製品名Anti-CENPT antibody
    CENPT 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CENPT
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 480 - 520 (LEMVEKCLDK YFQHLCDDLE VFAAHAGRKT VKPEDLELLM) of Human CENPT (NP_079358.3)

  • ポジティブ・コントロール
    • Whole cell lysate from HeLa cells or 293T cells.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab86595 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000 - 1/10000. Predicted molecular weight: 60 kDa.
IP Use at 10 µg/mg of lysate.

ターゲット情報

  • 機能Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENP-T is one of the basic inner kinetochore proteins with most further proteins binding downstream, suggesting a fundamental role of CENP-T in kinetochore function.
  • 配列類似性Belongs to the CENPT family.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Nucleus. Chromosome > centromere > kinetochore. Localizes exclusively in the kinetochore domain of centromeres.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C16orf56 antibody
    • CENP T antibody
    • CENP-T antibody
    • Cenpt antibody
    • CENPT_HUMAN antibody
    • Centromere protein T antibody
    • Chromosome 16 open reading frame 56 antibody
    • ICEN22 antibody
    • Interphase centromere complex protein 22 antibody
    see all

Anti-CENPT antibody 画像

  • All lanes : Anti-CENPT antibody (ab86595) at 0.1 µg/ml

    Lane 1 : Whole cell lysate from HeLa cells at 50 µg
    Lane 2 : Whole cell lysate from HeLa cells at 15 µg
    Lane 3 : Whole cell lysate from HeLa cells at 5 µg
    Lane 4 : Whole cell lysate from 293T cells at 50 µg


    Predicted band size : 60 kDa


    Exposure time : 3 minutes
  • 1mg whole cell lysate from Hela cells was immunoprecipited using 10ug ab86594.
    20% of IP was loaded per lane, and probed with ab86549 at 1ug/ml (lane 1) or with a control IgG (lane 2).
    Detection: hemiluminescence with an exposure time of 30 seconds.

Anti-CENPT antibody (ab86595) 使用論文

ab86595 has not yet been referenced specifically in any publications.

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