製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 配列
      HASSGKDVPECKTQ

特性

Our Abpromise guarantee covers the use of ab45476 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • CENP E
    • Centromere associated protein E
    • Centromere autoantigen E
    • Centromere autoantigen E (312kD)
    • Centromere protein E
    • Centromere protein E 312kDa
    • KIF10
    • Kinesin family member 10
    • Kinesin related protein
    • Kinesin related protein CENPE
    • PPP1R61
    • Protein phosphatase 1, regulatory subunit 61
    see all
  • 関連性
    CENPE is a 250-300 kDa human centromere-associated kinesin-like motor protein that accumulates in G2 phase. In contrast to other centromere proteins, CENPE is not detected at centromeres during interphase, and first appears at the centromere region of chromosomes during prometaphase. CENPE function is required for the transition from metaphase to anaphase. CENPE is probably one of the motors responsible for mammalian chromosome movement and/or spindle elongation.
  • 細胞内局在
    Associates with kinetochores during congression, relocates to the spindle midzone at anaphase, and is quantitatively discarded at the end of the cell division.

参考文献

ab45476 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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