製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to CED6
  • アプリケーション
    適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    EGTVFCLDPLDSRC

    , corresponding to C terminal amino acids 291-304 of Human CED6

  • ポジティブ・コントロール
    • Human kidney tissue; Human Placenta lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab85944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
IHC-P
  • 追加情報
    ELISA: 1/64000.
    IHC-P: Use at a concentration of 5 µg/ml.
    WB: Use at a concentration of 0.2 - 0.6 µg/ml for 1hr. Detects a band of approximately 35 kDa (predicted molecular weight: 35 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
    • 組織特異性
      Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary.
    • 配列類似性
      Belongs to the ced-6 family.
      Contains 1 PID domain.
    • 細胞内局在
      Cytoplasm. May associate with the cytoplasmic side of the plasma membrane and early endosomes.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CED6 antibody
      • Cell death protein 6 homolog antibody
      • Engulfment adapter protein antibody
      • Engulfment adaptor PTB domain containing 1 antibody
      • GULP antibody
      • GULP, engulfment adaptor PTB domain containing 1 antibody
      • GULP1 antibody
      • GULP1_HUMAN antibody
      • Protein GULP antibody
      • PTB domain adapter protein CED 6 antibody
      • PTB domain adapter protein CED-6 antibody
      • PTB domain adaptor protein CED6 antibody
      • PTB domain-containing engulfment adapter protein 1 antibody
      see all

    画像

    • ab85944 at 5µg/ml staining CED6 in human kidney by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.
    • Anti-CED6 antibody (ab85944) at 0.2 µg/ml + Human Placenta lysate at 30 µg

      Predicted band size : 35 kDa
      Observed band size : 35 kDa
      Additional bands at : 45 kDa. We are unsure as to the identity of these extra bands.

    参考文献

    ab85944 has not yet been referenced specifically in any publications.

    レビューと Q&A

    Thank you for your phone call.


    Our CED6 antibody ab85944 was raised against the synthetic peptide EGTVFCLDPLDSRC, corresponding to C terminal amino acids 291-304 of Human CED6. We recommend the following ELISA protocol:

    http:/...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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